双绒毛膜双羊膜囊双胎妊娠中的双胎输血综合征。
Twin-twin transfusion syndrome in a dizygotic monochorionic-diamniotic twin pregnancy.
作者信息
Quintero R A, Mueller O T, Martínez J M, Arroyo J, Gilbert-Barness E, Hilbelink D, Papenhausen P, Sutcliffe M
机构信息
Florida Institute for Fetal Diagnosis and Therapy, St. Joseph's Women's Hospital, Tampa, Florida, USA.
出版信息
J Matern Fetal Neonatal Med. 2003 Oct;14(4):279-81. doi: 10.1080/jmf.14.4.279.281.
We present a case of twin-twin transfusion syndrome with discordant gender. Monochorionicity was confirmed by surgical pathology. Cytogenetic analysis showed normal 46,XX and 46,XY karyotypes. Microsatellite analysis using reliable pericentromeric markers was consistent with dispermic fertilization of two separate ova. This suggests that monochorionicity, rather than zygosity, may be responsible for the development of placental vascular anastomoses.
我们报告一例性别不一致的双胎输血综合征病例。手术病理证实为单绒毛膜双胎。细胞遗传学分析显示核型正常，分别为46,XX和46,XY。使用可靠的着丝粒周围标记进行的微卫星分析与两个独立卵子的双精受精一致。这表明单绒毛膜性而非合子性可能是胎盘血管吻合发育的原因。
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