Guo Hongzhu, Koike Kazuo, Li Wei, Satou Tadaaki, Guo Dean, Nikaido Tamotsu
Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan.
J Nat Prod. 2004 Jan;67(1):10-3. doi: 10.1021/np0300131.
Five new saponins, mimengosides C-G (1-5), were isolated from the flower buds of Buddleja officinalis along with five known compounds, namely, songaroside A, acteoside, phenylethyl 2-glucoside, echinacoside, and phenylethyl alcohol 8-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside. The structures of 1-5 were elucidated using spectroscopic and chemical methods, and these compounds were evaluated for their inhibitory effects against HL-60 leukemia cells.
从密蒙花的花蕾中分离出5个新的皂苷，即密蒙皂苷C-G（1-5），同时还分离出5个已知化合物，分别为松果菊苷A、毛蕊花糖苷、苯乙醇2-O-β-D-葡萄糖苷、紫锥菊苷和苯乙醇8-O-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖苷。采用光谱学和化学方法阐明了1-5的结构，并对这些化合物对HL-60白血病细胞的抑制作用进行了评价。
