一例与特纳综合征相关的泛发性脓疱型银屑病。

A case of generalized pustular psoriasis associated with Turner syndrome.

作者信息

Kawakami Yoshio, Oyama Noritaka, Kishimoto Kazuhiro, Yamazaki Keiji, Nishibu Akiko, Nakamura Koichiro, Hoshi Satoshi, Kaneko Fumio

机构信息

Department of Dermatology, Fukushima Medical University School of Medicine, Fukushima, Japan.

出版信息

J Dermatol. 2004 Jan;31(1):16-20. doi: 10.1111/j.1346-8138.2004.tb00498.x.

DOI:10.1111/j.1346-8138.2004.tb00498.x

PMID:14739498

Abstract

UNLABELLED

We report a 27-year-old Japanese woman with Turner syndrome who had generalized pustular psoriasis of the von Zumbusch type. She developed a febrile diffuse erythema and pustular eruption without any history of preceding psoriasis vulgaris or drug ingestion. Oral treatment with 3.2 mg/kg cyclosporin per day successfully resulted in rapid improvement, followed by a complete remission. To our knowledge, this is the first report describing the unusual coexistence of these two systemic disorders. We discuss a hormone imbalance that might have contributed to the predisposition to pustular psoriasis and difficulties in the management of the patent's treatment.

ABBREVIATIONS

TS: Turner syndrome, GPP: generalized pustular psoriasis

摘要

未标注

我们报告一名27岁的日本特纳综合征女性患者，其患有泛发性脓疱型银屑病（冯·祖姆布施型）。她出现发热性弥漫性红斑和脓疱疹，既往无寻常型银屑病病史或药物摄入史。每天口服3.2毫克/千克环孢素治疗成功使病情迅速改善，随后完全缓解。据我们所知，这是首次描述这两种全身性疾病异常共存的报告。我们讨论了可能导致脓疱型银屑病易感性的激素失衡以及该患者治疗管理中的困难。