Vocks E, Worret W-I, Ring J
Department of Dermatology and Allergology Biederstein, Technical University of Munich, Munich, Germany.
J Eur Acad Dermatol Venereol. 2003 Jul;17(4):446-8. doi: 10.1046/j.1468-3083.2003.00715.x.
A case of erythema annulare centrifugum-type psoriasis in a 58-year-old white woman with a history of chronic plaque psoriasis is described. Initial failure of antipsoriatic treatments and an untypical histology complicated the diagnosis. After several trials acitretin at a low maintenance dose combined with oral fish oil and topical calcitriol led to sustained long-term remission. The spectrum of clinical differentiation of this rare disease, the histological characteristics and its nosological classification are discussed. It is suggested that this dermatosis represents a variant of acute psoriasis, rather than a variant of pustular psoriasis.
本文描述了一名58岁有慢性斑块状银屑病病史的白人女性患离心性环状红斑型银屑病的病例。抗银屑病治疗初期失败以及非典型组织学表现使诊断复杂化。经过多次试验,低维持剂量的阿维A联合口服鱼油和外用骨化三醇导致了长期持续缓解。讨论了这种罕见疾病的临床鉴别范围、组织学特征及其疾病分类。有人认为这种皮肤病是急性银屑病的一种变体,而不是脓疱型银屑病的变体。