Edwards J C, Carney D N, Daly P A, McCann S
Dept of Medical Operations, Boehringer Ingelheim Ltd., Dublin.
Ir Med J. 1992 Dec;85(4):151-2.
Serum calcium and albumin levels were measured in 255 patients with a confirmed diagnosis of malignant disease. The average serum calcium and albumin levels were similar to those reported in an earlier larger American survey. Only 6/255 patients were above the normal range of corrected serum calcium and one patient was sufficiently hypercalcaemic (corrected serum calcium at least 2.8 mmol/L) to be included in a trial of oral clodronate therapy. The incidence of hypercalcaemia in this survey is considerably lower than that reported in the published literature (5-10%). A much larger proportion of patients (21/255) were hypocalcaemic. Serum albumin was depressed in 25/255 cases and elevated in 2/255 cases.
对255例确诊为恶性疾病的患者进行了血清钙和白蛋白水平检测。血清钙和白蛋白的平均水平与美国早期一项规模更大的调查中报告的水平相似。255例患者中只有6例校正血清钙高于正常范围，1例患者高钙血症程度足以纳入口服氯膦酸盐治疗试验（校正血清钙至少2.8 mmol/L）。本次调查中高钙血症的发生率远低于已发表文献中报道的发生率（5%-10%）。有更大比例的患者（21/255）存在低钙血症。255例中有25例血清白蛋白降低，2例血清白蛋白升高。
