Ito M, Maruhashi M, Sakai N, Mizoue K, Hanada K
Research Center, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
J Antibiot (Tokyo). 1992 Oct;45(10):1559-65. doi: 10.7164/antibiotics.45.1559.
NG-011 and NG-012, novel potentiators of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542, together with 3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin. They potentiated the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12).