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NG-011 and NG-012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties.

作者信息

Ito M, Maruhashi M, Sakai N, Mizoue K, Hanada K

机构信息

Research Center, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.

出版信息

J Antibiot (Tokyo). 1992 Oct;45(10):1559-65. doi: 10.7164/antibiotics.45.1559.

Abstract

NG-011 and NG-012, novel potentiators of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542, together with 3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin. They potentiated the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12).

摘要

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