来自疣孢青霉的抗真菌大环多内酯类化合物。
Antifungal macrocyclic polylactones from Penicillium verruculosum.
作者信息
Breinholt J, Jensen G W, Nielsen R I, Olsen C E, Frisvad J C
机构信息
Novo Nordisk A/S, Plant Protection Division, Bagsvaerd, Denmark.
出版信息
J Antibiot (Tokyo). 1993 Jul;46(7):1101-8. doi: 10.7164/antibiotics.46.1101.
PMID:8360106
Abstract
Three macrocyclic polylactones have been isolated from Penicillium verruculosum. Two were found to be novel and the third to be identical with NG-012(1). Their structures were elucidated by spectroscopic and chemical methods. A full assignment of 1H- and 13C-resonances in acetone-d6 are given for all three compounds. The compounds show antifungal activity.
摘要
从疣孢青霉中分离出三种大环多内酯。其中两种被发现是新的，第三种与NG-012(1)相同。通过光谱和化学方法阐明了它们的结构。给出了所有三种化合物在氘代丙酮-d6中的1H和13C共振的完整归属。这些化合物具有抗真菌活性。
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