Okudaira Sayaka, Suzuki Shunji
Department of Obstetrics and Gynecology, Tokyo Rinkai Hospital, 1-4-2 Rinkai-cho, 134-0086 Edogawa-ku, Tokyo, Japan.
Arch Gynecol Obstet. 2005 Apr;271(4):292-5. doi: 10.1007/s00404-003-0594-6. Epub 2004 Jan 23.
We examined the relation between spinal hypotension (systolic blood pressure: <100 mmHg or <80% of the baseline value) and fetoplacental oxygen free radicals during elective cesarean section. Plasma xanthine, serum uric acid and plasma malondialdehyde levels in umbilical venous blood and blood gases in the umbilical artery were measured in patients receiving spinal anesthesia for elective cesarean section complicated with (n=26) and without (n=26) spinal hypotension. Patients with spinal hypotension were divided to two groups on the duration of the hypotension: those with the duration of <2 min (n=19) and those with the duration of > or =2 min (n=7).
There were no measurable differences in these variables between the control and the hypotension with the duration of <2 min groups. While, the plasma xanthine, serum uric acid and plasma malondialdehyde levels in the hypotension group with the duration of > or =2 min were significantly higher than those in the control group without the significant differences in blood gases and pH-levels.
我们在择期剖宫产期间研究了脊髓性低血压（收缩压：<100 mmHg或<基线值的80%）与胎儿胎盘氧自由基之间的关系。对择期剖宫产接受脊髓麻醉且并发（n = 26）和未并发（n = 26）脊髓性低血压的患者，测量其脐静脉血中的血浆黄嘌呤、血清尿酸和血浆丙二醛水平以及脐动脉中的血气。脊髓性低血压患者根据低血压持续时间分为两组：持续时间<2分钟的患者（n = 19）和持续时间≥2分钟的患者（n = 7）。
对照组与持续时间<2分钟的低血压组之间，这些变量没有可测量的差异。然而，持续时间≥2分钟的低血压组中的血浆黄嘌呤、血清尿酸和血浆丙二醛水平显著高于对照组，而血气和pH值无显著差异。
