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与自然感染的猪圆环病毒2型相关疾病有关的病理发现。

Pathological findings associated with naturally acquired porcine circovirus type 2 associated disease.

作者信息

Segalés Joaquim, Rosell Carles, Domingo Mariano

机构信息

Centre de Recerca en Sanitat Animal (CReSA), Departament de Sanitat i d'Anatomia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.

出版信息

Vet Microbiol. 2004 Feb 4;98(2):137-49. doi: 10.1016/j.vetmic.2003.10.006.

DOI:10.1016/j.vetmic.2003.10.006
PMID:14741126
Abstract

Porcine circovirus type 2 (PCV2) is a novel virus of the Circoviridae family which is considered the cause of postweaning multisystemic wasting syndrome (PMWS). PCV2 has also been associated to a number of pathological conditions of pigs, including porcine dermatitis and nephropathy syndrome, reproductive failure, porcine respiratory disease complex, proliferative and necrotising pneumonia and congenital tremor type AII. Pathological studies have been used to describe and characterise PMWS and these emerging conditions associated with PCV2. The objective of this review is to concentrate on the gross, microscopic and ultrastructural pathology associated with natural cases of PCV2 associated disease, along with some speculations on the pathogenesis of naturally occurring PMWS.

摘要

猪圆环病毒2型(PCV2)是圆环病毒科的一种新型病毒,被认为是断奶后多系统消耗综合征(PMWS)的病因。PCV2还与猪的多种病理状况有关,包括猪皮炎和肾病综合征、繁殖障碍、猪呼吸道疾病综合征、增生性和坏死性肺炎以及AII型先天性震颤。病理研究已用于描述和表征PMWS以及这些与PCV2相关的新出现的病症。本综述的目的是专注于与PCV2相关疾病自然病例相关的大体、微观和超微结构病理学,以及对自然发生的PMWS发病机制的一些推测。

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