Wise M G, Tierney J
Dept of Psychiatry, Ochsner Clinic, New Orleans.
J La State Med Soc. 1992 Oct;144(10):471-6.
By the year 2030, it is estimated that 17% of the population (52 million people) will be over age 65. Most of these individuals will be taking several medications, and one or more of these medications may be a psychotropic, that is, an antidepressant, anxiolytic, antipsychotic, or lithium. This article summarizes the pharmacokinetic changes that accompany aging and highlight how these changes impact the elderly.
据估计,到2030年,17%的人口(5200万人)将年满65岁。这些人中的大多数将服用多种药物,其中一种或多种药物可能是精神药物,即抗抑郁药、抗焦虑药、抗精神病药或锂盐。本文总结了衰老过程中伴随的药代动力学变化,并强调了这些变化如何影响老年人。