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人工大腿动静脉通路:采用SVS/AAVS报告标准的结果

Prosthetic thigh arteriovenous access: outcome with SVS/AAVS reporting standards.

作者信息

Cull John D, Cull David L, Taylor Spence M, Carsten Christopher G, Snyder Bruce A, Youkey Jerry R, Langan Eugene M, Blackhurst Dawn W

机构信息

Department of Surgery, Greenville Hospital System, Greenville, SC 29605, USA.

出版信息

J Vasc Surg. 2004 Feb;39(2):381-6. doi: 10.1016/s0741-5214(03)00720-1.

Abstract

PURPOSE

Differences in the reporting methods of results for arteriovenous (AV) access can dramatically affect apparent outcome. To enable meaningful comparisons in the literature, the Society for Vascular Surgery and the American Association for Vascular Surgery (SVS/AAVS) recently published reporting standards for dialysis access. The purpose of the present study was to determine infection rates, patency rates, and possible predictive factors for prosthetic thigh AV access outcomes with the reporting standards of the SVS/AAVS.

METHODS

A retrospective analysis was performed of all patients who underwent placement of thigh AV access by the Surgical Teaching Service at Greenville Memorial Hospital between 1989 and 2001. Outcomes were determined based on SVS/AAVS Standards for Reports Dealing with AV Accesses. The rate of revision per year of access patency was also determined; this end point more accurately reflects the true cost and morbidity associated with AV access than do patency or infection rates alone.

RESULTS

One hundred twenty-five polytetrafluoroethylene thigh AV accesses were placed in 100 patients. Nine accesses were excluded from the study, six because there was no patient follow-up and 3 as a result of deaths unrelated to the access procedure and which occurred less than 30 days after access placement. There were six (4%) late access-related deaths. There were 18 (15%) early access failures, related to infection in 14 cases (12%), thrombosis in three cases (2%), and steal in one case (1%). Early failure was more common in patients with diabetes mellitus (P =.036). The primary and secondary functional patency rates were 19% and 54%, respectively, at 2 years. Infection occurred in 48 (41%) accesses. The patency and infection rates were not influenced by patient age, gender, body mass index, or diabetes mellitus. The median number of interventions per year of access patency was 1.68, and this outcome was positively correlated with body mass index (P <.001).

CONCLUSIONS

Prosthetic AV access in the thigh is associated with higher morbidity compared with that reported for the upper extremity, and should be considered only if no upper extremity AV access option is available. Early access failure and the requirement for an increased number of interventions to reestablish and maintain access patency are more common in patients with diabetes mellitus and obesity. The number of interventions per year of access patency is a valuable end point when assessing the outcome of AV access procedures.

摘要

目的

动静脉(AV)通路结果报告方法的差异会显著影响表面上的结果。为了在文献中进行有意义的比较,血管外科学会和美国血管外科学会(SVS/AAVS)最近发布了透析通路的报告标准。本研究的目的是根据SVS/AAVS的报告标准确定人工大腿AV通路的感染率、通畅率以及可能的预测因素。

方法

对1989年至2001年间在格林维尔纪念医院外科教学服务部接受大腿AV通路置入的所有患者进行回顾性分析。根据SVS/AAVS关于AV通路报告的标准确定结果。还确定了通路通畅每年的翻修率;与单独的通畅率或感染率相比,这个终点能更准确地反映与AV通路相关的真实成本和发病率。

结果

100例患者置入了125条聚四氟乙烯大腿AV通路。9条通路被排除在研究之外,6条是因为没有患者随访,3条是由于与通路手术无关且在通路置入后不到30天发生的死亡。有6例(4%)与通路相关的晚期死亡。有18例(15%)早期通路失败,14例(12%)与感染有关,3例(2%)与血栓形成有关,1例(1%)与窃血有关。早期失败在糖尿病患者中更常见(P = 0.036)。2年时的主要和次要功能通畅率分别为19%和54%。48条(41%)通路发生感染。通畅率和感染率不受患者年龄、性别、体重指数或糖尿病的影响。通路通畅每年的干预中位数为1.68,这一结果与体重指数呈正相关(P < 0.001)。

结论

与上肢相比,大腿人工AV通路的发病率更高,只有在上肢没有AV通路选择时才应考虑。早期通路失败以及为重建和维持通路通畅而需要增加干预次数在糖尿病和肥胖患者中更常见。通路通畅每年的干预次数是评估AV通路手术结果时一个有价值的终点。

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