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下肢动静脉内瘘用于血液透析的长期疗效

Long Term Outcomes of Arteriovenous Grafts for Hemodialysis in Lower Extremities.

作者信息

Han Seok, Song Dan, Yun Sangchul

机构信息

Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea.

出版信息

Vasc Specialist Int. 2016 Dec;32(4):180-185. doi: 10.5758/vsi.2016.32.4.180. Epub 2016 Dec 31.

Abstract

PURPOSE

The lower extremity has received its fair share of attention as a vascular access site in patients who have exhausted their upper arm vessels. However, experiences with lower extremity arteriovenous grafts (AVGs) have so far been disappointing because of high infection rates and severe limb ischemia. We report our experience with hemodialysis access from the lower extremity.

MATERIALS AND METHODS

A retrospective review of 60 lower extremity AVGs created between January 2003 and December 2011 was performed. Age, sex, etiology of end-stage renal disease and complications were tabulated. Primary and secondary patency rates were determined.

RESULTS

The average age of the study population was 56 years and 38 patients were female. Renal failure was associated with hypertension in 40 (66.7%) patients, diabetes in 28 (46.7%) patients and cardiovascular disease in 9 (15.0%) patients. The follow-up period was 8-108 months. Fifty-four patients had bilateral central vein stenosis. Seven (11.7%) patients had primary failure of their AVG. There was no operation-related death. Primary and secondary patency rates were: 66% and 90% at 1 year, 40% and 90% at 2 years, 27% and 87% at 3 years, and 18% and 87% at 5 years, respectively. There were 105 postoperative complications that developed in 67 patients. Postoperative complications were: thrombosis (30), proximal vein stenosis (56), infection (9), bleeding with hematoma (1), perigraft seroma (3), steal syndrome (2), and pseudoaneurysm (4).

CONCLUSION

A lower extremity AVG seems to be a viable option in patients with unusable upper extremity veins.

摘要

目的

下肢作为血管通路部位,在那些上臂血管已无法使用的患者中已受到了应有的关注。然而,由于感染率高和严重肢体缺血,下肢动静脉移植物(AVG)的应用经验至今仍不尽人意。我们报告我们在下肢建立血液透析通路的经验。

材料与方法

对2003年1月至2011年12月期间建立的60例下肢AVG进行回顾性研究。记录患者的年龄、性别、终末期肾病病因及并发症情况。确定初次通畅率和二次通畅率。

结果

研究人群的平均年龄为56岁,女性38例。40例(66.7%)患者的肾衰竭与高血压相关,28例(46.7%)与糖尿病相关,9例(15.0%)与心血管疾病相关。随访时间为8 - 108个月。54例患者存在双侧中心静脉狭窄。7例(11.7%)患者的AVG初次使用失败。无手术相关死亡病例。初次通畅率和二次通畅率分别为:1年时66%和90%,2年时40%和90%,3年时27%和87%,5年时18%和87%。67例患者共发生105例术后并发症。术后并发症包括:血栓形成(30例)、近端静脉狭窄(56例)、感染(9例)、出血伴血肿(1例)、移植物周围血清肿(3例)、窃血综合征(2例)和假性动脉瘤(4例)。

结论

对于上肢静脉无法使用的患者,下肢AVG似乎是一种可行的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaae/5198765/5ccf7298fe6f/vsi-32-180f1.jpg

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