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表现为恶性外耳道炎的颞骨癌

Carcinoma of temporal bone presenting as malignant otitis externa.

作者信息

al-Shihabi B A

机构信息

Royal National Throat, Nose and Ear Hospital, London.

出版信息

J Laryngol Otol. 1992 Oct;106(10):908-10. doi: 10.1017/s0022215100121255.

DOI:10.1017/s0022215100121255
PMID:1474316
Abstract

A 69-year-old man presented with a three-month history of otalgia and tenderness of the right ear and a one-week history of a painful right parotid swelling. Examination revealed granulation tissue in the right ear canal with normal looking tympanic membranes and a parotid abscess. Repeated biopsies from the ear canal and parotid showed non-specific inflammation. Repeated cultures from both areas grew Ps. aeruginosa. The patient's condition improved following three weeks of intensive treatment for malignant otitis externa only to relapse five weeks after the end of treatment. He received a second course, only to improve temporarily. He developed a right facial nerve palsy five weeks after he was first seen, followed four months later by palsies of all cranial nerves except the olfactory, before dying, seven months after his first appointment. The radiological, histological and post-mortem findings are discussed.

摘要

一名69岁男性,有3个月的右耳耳痛及压痛病史,以及1周的右侧腮腺肿痛病史。检查发现右侧耳道有肉芽组织,鼓膜外观正常,并有腮腺脓肿。耳道和腮腺的多次活检显示为非特异性炎症。两个部位的多次培养均培养出铜绿假单胞菌。该患者在接受了3周的恶性外耳道炎强化治疗后病情好转,但在治疗结束5周后复发。他接受了第二个疗程的治疗,只是暂时有所改善。首次就诊5周后,他出现了右侧面神经麻痹,4个月后,除嗅觉神经外的所有颅神经均出现麻痹,首次就诊7个月后死亡。本文讨论了影像学、组织学及尸检结果。

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Cureus. 2022 Nov 28;14(11):e31973. doi: 10.7759/cureus.31973. eCollection 2022 Nov.
2
Squamous cell carcinoma of the external auditory canal in a patient with non-resolving ear discharge.一名患有持续性耳漏的患者外耳道鳞状细胞癌
Malays Fam Physician. 2015 Aug 31;10(2):52-4. eCollection 2015.
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Malignant tumors of the temporal bone - our experience.颞骨恶性肿瘤——我们的经验
Braz J Otorhinolaryngol. 2016 Jul-Aug;82(4):479-83. doi: 10.1016/j.bjorl.2015.09.010. Epub 2016 Jan 7.
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Primary squamous cell carcinoma of the external auditory canal: surgical treatment and long-term outcomes.外耳道原发性鳞状细胞癌:手术治疗及长期疗效
Acta Otorhinolaryngol Ital. 2014 Apr;34(2):129-37.