一名曾有顺铂诱导耳毒性的患者出现红霉素相关听力损失。
Erythromycin associated hearing loss in a patient with prior cis-platinum induced ototoxicity.
作者信息
Wallach P M, Love S R, Fiorica J V, Hoffman M S, Flannery M T
机构信息
Department of Internal Medicine, University of South Florida College of Medicine, Tampa.
出版信息
J Fla Med Assoc. 1992 Dec;79(12):821-2.
PMID:1474367
Abstract
A case is reported of reversible sensorineural hearing loss associated with intravenous erythromycin treatment. Cis-platinum induced high frequency hearing loss developed nine months previously during treatment for stage IV papillary cystadenocarcinoma. Renal and hepatic function were normal; however, serum erythromycin levels were elevated. Clinical recovery promptly followed discontinuation of erythromycin.
摘要
报告了1例与静脉注射红霉素治疗相关的可逆性感音神经性听力损失病例。顺铂诱发的高频听力损失在9个月前IV期乳头状囊腺癌治疗期间出现。肾功能和肝功能正常；然而，血清红霉素水平升高。停用红霉素后临床迅速恢复。
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