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[膳食植物雌激素及其对成年人类健康的潜在益处]

[Dietary phytoestrogen and its potential benefits in adult human health].

作者信息

Garrido Argelia, de la Maza María Pía, Valladares Luis

机构信息

Laboratorio de Hormonas-Receptores y Laboratorio de Lípidos-Antioxidantes, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile.

出版信息

Rev Med Chil. 2003 Nov;131(11):1321-8.

Abstract

Human diet contains a series of bioactive vegetal compounds that can improve human health. Among these, there has been a special interest for phytoestrogens. This article reviews the evidence about the potential benefits of phytoestrogens for human health. Forty eight manuscripts were selected for their study design and relevance to human health. The cell growth inhibitory effects of phytoestrogens and their implication in breast cancer are reviewed. Also the effects of these compounds on serum lipid levels and the effectiveness of a phytoestrogen derivate, ipriflavone, on the prevention of osteoporosis are analyzed. Although these compounds have a great potential for improving health, there is still not enough evidence to recommend the routine use of phytoestrogens.

摘要

人类饮食中含有一系列具有生物活性的植物化合物,这些化合物可以改善人类健康。其中,植物雌激素受到了特别关注。本文综述了植物雌激素对人类健康潜在益处的相关证据。根据研究设计和与人类健康的相关性,挑选了48篇手稿。综述了植物雌激素的细胞生长抑制作用及其在乳腺癌中的意义。还分析了这些化合物对血清脂质水平的影响以及一种植物雌激素衍生物依普黄酮预防骨质疏松症的有效性。尽管这些化合物在改善健康方面具有很大潜力,但仍没有足够的证据推荐常规使用植物雌激素。

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