Leitgeb Rainer A, Schmetterer Leopold, Hitzenberger Christoph K, Fercher Adolf F, Berisha Fatma, Wojtkowski Maciej, Bajraszewski Tomasz
Department of Medical Physics, University of Vienna, Waehringer Strasse 13, Vienna A-1090, Austria.
Opt Lett. 2004 Jan 15;29(2):171-3. doi: 10.1364/ol.29.000171.
The possibility of measuring a full Doppler flow depth profile in parallel by use of frequency-domain optical coherence tomography is demonstrated. The method is based on a local phase analysis of the backscattered signal and allows for imaging of bidirectional Doppler flow. The Doppler frequency limit is 5 kHz for the presented measurements and is set by half of the frame rate of the CCD detector array. We measured the flow of 0.3-microm microspheres suspended in distilled water at controlled flow rates and in vitro human blood flow through a 200-microm capillary with a real-time color-encoded Doppler tomogram rate of 2-3/s.
本文展示了利用频域光学相干断层扫描技术并行测量完整多普勒血流深度剖面的可能性。该方法基于对背向散射信号的局部相位分析，能够对双向多普勒血流进行成像。在目前的测量中，多普勒频率极限为5kHz，由电荷耦合器件（CCD）探测器阵列帧率的一半设定。我们以2 - 3次/秒的实时彩色编码多普勒断层扫描速率，测量了以可控流速悬浮在蒸馏水中的0.3微米微球的流动情况以及体外人血液通过200微米毛细血管的流动情况。
