Kempainen Robert R, Brunette Douglas D
Department of Medicine, Fairview University Medical Center, Minneapolis, Minnesota, USA.
Respir Care. 2004 Feb;49(2):192-205.
Accidental hypothermia is defined as an unintentional decrease in core body temperature to below 35 degrees C. Hypothermia causes hundreds of deaths in the United States annually. Victims of accidental hypothermia present year-round and in all climates with a potentially confusing array of signs and symptoms, but increasing severity of hypothermia produces a predictable pattern of systemic organ dysfunction and associated clinical manifestations. The management of hypothermic patients differs in several important respects from that of euthermic patients, so advance knowledge about hypothermia is prerequisite to optimal management. The paucity of randomized clinical trials with hypothermic patients precludes creation of evidence-based treatment guidelines, but a clinically sound management strategy, tailored to individual patient characteristics and institutional expertise and resources, can nonetheless be gleaned from the literature. This article reviews the epidemiology, pathophysiology, clinical presentation, and treatment of accidental hypothermia. Initial evaluation and stabilization, selection of a rewarming strategy, and criteria for withholding or withdrawing support are discussed.
意外低温是指核心体温无意下降至35摄氏度以下。在美国,低温每年导致数百人死亡。意外低温的受害者全年都有,在所有气候条件下都可能出现一系列令人困惑的体征和症状,但随着低温程度的加重,会出现可预测的全身器官功能障碍模式及相关临床表现。低温患者的管理在几个重要方面与体温正常的患者不同,因此,对低温的预先了解是实现最佳管理的先决条件。针对低温患者的随机临床试验较少,无法制定基于证据的治疗指南,但从文献中仍可提炼出一种根据患者个体特征以及机构专业知识和资源量身定制的合理临床管理策略。本文综述了意外低温的流行病学、病理生理学、临床表现及治疗。讨论了初始评估与稳定、复温策略的选择以及停止或撤回支持的标准。