Kangasniemi Marko, Mäkelä Teppo, Koskinen Seppo, Porras Matti, Poussa Kristiina, Hernesniemi Juha
Department of Radiology, Helsinki University Central Hospital, Helsinki, Finland.
Neurosurgery. 2004 Feb;54(2):336-40; discussion 340-1. doi: 10.1227/01.neu.0000103448.07132.e1.
Computed tomographic angiography (CTA) has become a diagnostic method for the detection of intracranial aneurysms in cases of subarachnoid bleeding. We sought to evaluate the detection of aneurysms with CTA with a novel multislice helical computed tomographic scanner.
Prospectively, 179 patients underwent multislice CTA, followed by digital subtraction angiography (DSA) of both carotid arteries with or without the posterior circulation, DSA of one carotid artery with or without the posterior circulation, or DSA of the posterior circulation alone. The total number of carotid arteries studied was 298, and the number of vertebrobasilar arteries studied was 124.
Of 178 aneurysms verified with DSA or intraoperatively, CTA failed to detect 7 aneurysms of 1 to 2 mm and 1 partially thrombosed, 4-mm aneurysm. The sensitivity and specificity of CTA for aneurysm detection were 0.96 and 0.97, respectively.
The first generation of multislice computed tomographic technology does not improve CTA to surpass DSA for the detection of small aneurysms of 1 to 2 mm. In practice, however, CTA is superior as a fast noninvasive method without complications.
计算机断层血管造影(CTA)已成为蛛网膜下腔出血病例中检测颅内动脉瘤的一种诊断方法。我们试图用一种新型多层螺旋计算机断层扫描仪评估CTA对动脉瘤的检测情况。
前瞻性地对179例患者进行了多层CTA检查,随后对双侧颈动脉进行数字减影血管造影(DSA),检查后循环血管与否,或仅对一侧颈动脉进行DSA检查(检查后循环血管与否),或仅对后循环血管进行DSA检查。研究的颈动脉总数为298条,研究的椎基底动脉数量为124条。
在经DSA或手术证实的178个动脉瘤中,CTA未能检测出7个1至2毫米的动脉瘤以及1个部分血栓形成的4毫米动脉瘤。CTA检测动脉瘤的敏感性和特异性分别为0.96和0.97。
第一代多层计算机断层扫描技术在检测1至2毫米的小动脉瘤方面,并未使CTA的检测效果超越DSA。然而,在实际应用中,CTA作为一种快速、无创且无并发症的方法具有优势。