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选择性免疫球蛋白A缺乏症和常见可变免疫缺陷症患者的口腔状况

Oral conditions in individuals with selective immunoglobulin A deficiency and common variable immunodeficiency.

作者信息

Engström G N, Engström P E, Hammarström L, Smith C I

机构信息

Department of Periodontology, Karolinska Institute, Huddinge Hospital, Sweden.

出版信息

J Periodontol. 1992 Dec;63(12):984-9. doi: 10.1902/jop.1992.63.12.984.

DOI:10.1902/jop.1992.63.12.984
PMID:1474470
Abstract

Saliva and serum samples were collected from 36 individuals with selective immunoglobulin A deficiency (IgAd) and 23 patients with common variable immunodeficiency (CVI). The oral examination included registration of the teeth, Russell's periodontal index (PI), pocket formation, and salivary flow rate in both unstimulated and stimulated saliva. No differences were found in salivary flow rate, number of teeth, or pocket depth when donors with IgAd or CVI were compared to age and sex matched controls. However, mucosal manifestations of lichenoid type were more frequent in both types of immunoglobulin deficient individuals. An increased PI was also seen in CVI patients. Increased serum IgG and salivary IgM levels were found in the IgAd population.

摘要

收集了36例选择性免疫球蛋白A缺乏症(IgAd)患者和23例常见可变免疫缺陷症(CVI)患者的唾液和血清样本。口腔检查包括牙齿登记、罗素牙周指数(PI)、牙周袋形成以及非刺激性和刺激性唾液的唾液流速。将IgAd或CVI患者与年龄和性别匹配的对照组进行比较时,在唾液流速、牙齿数量或牙周袋深度方面未发现差异。然而,两种类型的免疫球蛋白缺乏个体中,苔藓样型的黏膜表现更为常见。CVI患者的PI也有所增加。在IgAd人群中发现血清IgG和唾液IgM水平升高。

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Oral conditions in individuals with selective immunoglobulin A deficiency and common variable immunodeficiency.选择性免疫球蛋白A缺乏症和常见可变免疫缺陷症患者的口腔状况
J Periodontol. 1992 Dec;63(12):984-9. doi: 10.1902/jop.1992.63.12.984.
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J Clin Med. 2024 Aug 27;13(17):5079. doi: 10.3390/jcm13175079.
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Periodontal and other oral manifestations of immunodeficiency diseases.免疫缺陷病的牙周及其他口腔表现。
Oral Dis. 2017 Oct;23(7):866-888. doi: 10.1111/odi.12584. Epub 2016 Oct 10.
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Salivary defense factors and oral health in patients with common variable immunodeficiency.普通可变免疫缺陷患者的唾液防御因子与口腔健康
J Clin Immunol. 1994 Jul;14(4):229-36. doi: 10.1007/BF01552309.