立体定向高频刺激小脑前叶在脑瘫治疗中的作用：一种新的枕下入路

Effect of stereotactic high-frequency stimulation in the anterior lobe of the cerebellum in cerebral palsy: a new suboccipital approach.

作者信息

Galanda M, Horvath S

机构信息

Department of Neurosurgery, Roosevelt Hospital, Banska Bystrica, Slovakia.

出版信息

Stereotact Funct Neurosurg. 2003;80(1-4):102-7. doi: 10.1159/000075168.

DOI:10.1159/000075168

PMID:14745217

Abstract

The direct stereotactic suboccipital approach to the anterior lobe of the cerebellum was applied for deep high-frequency stimulation in three patients (for 29, 8 and 3 months) suffering from cerebral palsy. In agreement with our previous experience with a transtentorial approach in 30 patients, spasticity, dyskinesias and behavior were improved during chronic intermittent stimulation (frequency 185 Hz, pulse width 210 micros, voltage individually altered according to motor response at 0.5-4.0 V, 15 min on, 2-6 h off). Patients attained useful motor skill improvements. The results indicate that the method is safe, effective and reasonable.

摘要

对3例脑瘫患者采用直接立体定向枕下小脑前叶入路进行深部高频刺激（分别刺激29个月、8个月和3个月）。与我们之前对30例患者采用经小脑幕入路的经验一致，在慢性间歇性刺激期间（频率185Hz，脉宽210微秒，电压根据运动反应在0.5 - 4.0V个体化调整，开启15分钟，关闭2 - 6小时），痉挛、运动障碍和行为得到改善。患者的运动技能有了有效的提高。结果表明该方法安全、有效且合理。