Gaspar Nikolas, Kilarski Laura Luisa, Rosen Helena, Huppertz Maximilian, Philipsen Alexandra, Rohner Henrik
Department of Psychiatry and Psychotherapy, Faculty of Medicine, University of Bonn, 53111 Bonn, Germany.
J Clin Med. 2024 Jun 3;13(11):3301. doi: 10.3390/jcm13113301.
: Substance use disorders present a tremendous challenge within contemporary healthcare systems. Specifically, in the domain of opioid use disorders (OUDs), several foundational elements are crucial for the efficacious management of afflicted individuals. Regrettably, the premature discontinuation of inpatient opioid withdrawal treatment is a prevalent phenomenon. This study aims to elucidate the prevalence of the premature termination of inpatient opioid withdrawal treatment among patients with comorbid ADHD. : We conducted a comprehensive assessment of all participants currently undergoing inpatient opioid withdrawal treatment. Our assessment protocol included the administration of the ADHD Self-Report Scale (ADHD-SR) and the Wender Utah Rating Scale (WURS-k). Additionally, participants who met the thresholds on one or both questionnaires underwent further evaluation using the Diagnostic Interview for ADHD in Adults (DIVA-2.0). : The prevalence of individuals diagnosed with ADHD within the studied cohort was determined to be 29.3%. Among the subset of participants identified as ADHD-positive, a notable 54.5% prematurely ceased therapy. In contrast, among those identified as ADHD-negative, the premature discontinuation rate was substantially lower at 28.3%. : In summary, the impact of ADHD as a comorbid condition on the efficacy of inpatient opioid withdrawal treatment has been underscored. By identifying comorbid ADHD early in the treatment process, tailored therapeutic approaches may help to maximize the effectiveness of interventions and may improve patient outcomes. This underscores the importance of proactive screening for ADHD as a psychiatric comorbidity in optimizing the management of individuals undergoing inpatient opioid withdrawal treatment.
物质使用障碍在当代医疗系统中构成了巨大挑战。具体而言,在阿片类物质使用障碍(OUDs)领域,几个基本要素对于有效管理患者至关重要。遗憾的是,住院阿片类物质戒断治疗的提前终止是一种普遍现象。本研究旨在阐明合并注意力缺陷多动障碍(ADHD)患者中住院阿片类物质戒断治疗提前终止的发生率。
我们对所有正在接受住院阿片类物质戒断治疗的参与者进行了全面评估。我们的评估方案包括使用ADHD自我报告量表(ADHD-SR)和温德犹他评定量表(WURS-k)。此外,在一份或两份问卷上达到阈值的参与者使用成人ADHD诊断访谈(DIVA-2.0)进行进一步评估。
在所研究的队列中,被诊断为ADHD的个体发生率为29.3%。在被确定为ADHD阳性的参与者子集中,显著有54.5%提前停止治疗。相比之下,在被确定为ADHD阴性的参与者中,提前停药率则低得多,为28.3%。
总之,ADHD作为一种共病情况对住院阿片类物质戒断治疗疗效的影响已得到强调。通过在治疗过程早期识别合并的ADHD,量身定制的治疗方法可能有助于最大限度地提高干预效果,并可能改善患者预后。这凸显了在优化住院阿片类物质戒断治疗个体管理中,主动筛查ADHD作为一种精神共病的重要性。