Wright J W, Kern M D
Department of Psychology, Washington State University, Pullman 99164.
J Morphol. 1992 Dec;214(3):299-320. doi: 10.1002/jmor.1052140306.
We present a stereotaxic atlas of the brain of the trumpet-tailed rat or degu (Octodon degus), an hystricomorph rodent native to Chile and one which has become increasingly popular as a research animal, among other things because of its use as a model for diabetic cataracts and its tendency to become hyperglycemic. The atlas contains 38 transverse and two sagittal sections of the brain covering pros-, mes-, and rhombencephalon, as well as diagrams of the brain's surface anatomy. It was constructed from brains of young adult male degus but can be used readily in studies of adult females, since there is no apparent sexual dimorphism in the brain size of this rodent. Ninety percent of 40 experimental lesions used to check the accuracy of the atlas were correctly placed. The fore- and midbrain of the degu are generally more compact than corresponding regions of the brain in the laboratory rat (suborder Myomorpha) and the guinea pig (another hystricomorph). The amygdaloid complex extends further forward in the telencephalon. Major mesencephalic nuclei and fiber tracts are more rostral in position. However, superior and inferior colliculi are much longer in degus than rats. The basic organization of the rhombencephalon is similar in degus and rats, although there are clearcut differences in the length or size of some hindbrain nuclei.
我们展示了一份喇叭尾鼠或八齿鼠(Octodon degus)大脑的立体定位图谱,八齿鼠是一种原产于智利的豪猪型啮齿动物,因其作为糖尿病性白内障模型的用途以及易患高血糖症等原因,越来越多地成为一种受欢迎的实验动物。该图谱包含38个大脑横切面和2个矢状切面,覆盖前脑、中脑和后脑,以及大脑表面解剖图。它是根据成年雄性八齿鼠的大脑构建的,但由于这种啮齿动物的大脑大小没有明显的性别二态性,因此也可很容易地用于成年雌性的研究。用于检验图谱准确性的40个实验性损伤中,90%放置正确。八齿鼠的前脑和中脑通常比实验室大鼠(鼠形亚目)和豚鼠(另一种豪猪型动物)大脑的相应区域更紧凑。杏仁复合体在端脑中向前延伸得更远。中脑主要核团和纤维束的位置更靠前。然而,八齿鼠的上丘和下丘比大鼠长得多。八齿鼠和大鼠后脑的基本组织结构相似,尽管一些后脑核团的长度或大小存在明显差异。