Klesius Armin Alex, Dzemali Omer, Simon Andreas, Kleine Peter, Abdel-Rahman Ulf, Herzog Christopher, Wimmer-Greinecker Gerhard, Moritz Anton
Department of Cardiovascular and Thoracic Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Theodor-Stern-Kai 7, 60596, Frankfurt, Germany.
Eur J Cardiothorac Surg. 2004 Feb;25(2):218-23. doi: 10.1016/j.ejcts.2003.11.019.
Severe sternum necrosis requiring extended resection necessitates plastic reconstruction of the resulting defect and stabilization of the chest. We analyzed the outcome of patients undergoing bilateral pectoralis major flap repair on functional and cosmetic results, chest stabilization and pulmonary function.
Twelve patients undergoing cardiac surgery between 1997 and 2001 suffered from a deep mediastinal wound infection and sternum necrosis. After a mean of two attempts of extensive wound debridement, all 12 patients underwent complete sternal resection with plastic reconstruction by bilateral pectoralis major flaps. Risk factors were obesity (n=10) and diabetes (n=11). Six months postoperatively patients underwent physical examination, pulmonary function testing and functional CT scan.
Three patients died in hospital (two septic multiorgan failure, one heart failure) and nine were discharged with complete wound closure. One patient suffered a lethal stroke during follow-up. At 6-month follow-up no recurrent sternum infection had occurred. Chest stability was satisfactory without impairment of pulmonary function (VC 77.5+/-12.1% at follow-up vs 77.8+/-12.5% preoperatively). Mobility and force of arms and shoulder were adequate; at CT scan the maximum distance change between the former sternoclavicular joint in inspiration versus expiration was minimal. Quality of life questionnaires showed no significant limitations except a disturbed sleep and mild restriction of executing hobbies and social activities.
Bilateral pectoralis major flap repair is a safe technique to cure severe mediastinitis necessitating complete sternal resection. Wounds close without extensive reconstructive surgery. Cosmetic results as well as stabilization of the chest were good. Patients reported an almost uncompromised quality of life without respiratory impairment.
严重的胸骨坏死需要进行扩大切除,这就需要对 resulting defect 进行整形修复并稳定胸部。我们分析了接受双侧胸大肌皮瓣修复的患者在功能和美容效果、胸部稳定及肺功能方面的结果。
1997年至2001年间接受心脏手术的12例患者发生了深部纵隔伤口感染和胸骨坏死。在平均进行了两次广泛伤口清创术后,所有12例患者均接受了完整的胸骨切除,并采用双侧胸大肌皮瓣进行整形修复。危险因素包括肥胖(n = 10)和糖尿病(n = 11)。术后6个月对患者进行体格检查、肺功能测试和功能性CT扫描。
3例患者在医院死亡(2例因感染性多器官功能衰竭,1例因心力衰竭),9例患者伤口完全愈合出院。1例患者在随访期间发生致命性中风。在6个月的随访中,未发生复发性胸骨感染。胸部稳定性良好,肺功能未受损害(随访时肺活量为77.5±12.1%,术前为77.8±12.5%)。手臂和肩部的活动度和力量足够;CT扫描显示,吸气与呼气时原胸锁关节之间的最大距离变化最小。生活质量问卷显示,除睡眠障碍以及执行爱好和社交活动受到轻度限制外,无明显限制。
双侧胸大肌皮瓣修复是治疗需要完整胸骨切除的严重纵隔炎的一种安全技术。无需广泛的重建手术即可闭合伤口。美容效果以及胸部稳定性良好。患者报告生活质量几乎不受影响,且无呼吸功能损害。