Puska Päivi, Harju Mika, Liebkind Ron
Helsinki University Eye Hospital, Haartmaninkatu 4 C, PO Box 220, 00029, HYKS, Finland.
Graefes Arch Clin Exp Ophthalmol. 2004 Apr;242(4):301-5. doi: 10.1007/s00417-003-0843-1. Epub 2004 Jan 28.
To compare the areas of peripapillary atrophy between fellow eyes in patients with unilateral exfoliation syndrome.
Topographic measurements for peripapillary atrophy and the optic nerve head with confocal scanning laser ophthalmoscopy, using the Heidelberg Retina Tomograph were performed on 45 nonglaucomatous patients with unilateral exfoliation syndrome. The area of peripapillary atrophy was divided into an alpha and a beta zone. The areas of alpha and beta peripapillary atrophy and their angular extents around the disc were measured. The frequency distributions of the alpha and beta areas and their largest radial extents at different positions around the disc were calculated.
An alpha area was detected in 84% of the exfoliative and 89% of the nonexfoliative fellow eyes, and a beta area in 31% and 42% of eyes, respectively. The exfoliative and the fellow nonexfoliative eyes did not differ in the sizes of the alpha (0.43+/-0.46 vs 0.33+/-0.18 mm(2), P=0.68) and beta (0.14+/-0.30 vs 0.17+/-0.34 mm(2), P=0.96) areas of peripapillary atrophy. The angular extents, the locations of the largest radial extent, and the frequency distributions of the alpha and beta peripapillary atrophy areas were similar in fellow eyes.
Exfoliation syndrome itself is not a risk factor for peripapillary atrophy.
比较单侧剥脱综合征患者患眼与对侧眼的视乳头周围萎缩面积。
使用海德堡视网膜断层扫描仪，通过共焦扫描激光眼底镜对视乳头周围萎缩和视神经乳头进行地形图测量，对45例非青光眼性单侧剥脱综合征患者进行检查。视乳头周围萎缩区域分为α区和β区。测量α区和β区视乳头周围萎缩的面积及其在视盘周围的角度范围。计算α区和β区面积及其在视盘周围不同位置的最大径向范围的频率分布。
在84%的剥脱性对侧眼和89%的非剥脱性对侧眼中检测到α区，在31%和42%的眼中检测到β区。剥脱性眼和对侧非剥脱性眼在视乳头周围萎缩的α区（0.43±0.46 vs 0.33±0.18 mm²，P = 0.68）和β区（0.14±0.30 vs 0.17±0.34 mm²，P = 0.96）大小上无差异。对侧眼在α区和β区视乳头周围萎缩的角度范围、最大径向范围位置以及频率分布相似。
剥脱综合征本身不是视乳头周围萎缩的危险因素。
