Hawley John A, Zierath Juleen R
Exercise Metabolism Group, School of Medical Sciences, RMIT University, Bundoora, Victoria, Australia.
Exerc Sport Sci Rev. 2004 Jan;32(1):4-8. doi: 10.1097/00003677-200401000-00002.
Exercise has diverse effects on metabolic and mitogenic signaling pathways in human skeletal muscle, implying specificity of intracellular signaling cascades. The role of several parallel signaling cascades are discussed in an effort to assign a physiological role for these targets in the regulation of exercise-mediated responses on metabolism and gene expression.
运动对人类骨骼肌的代谢和有丝分裂信号通路具有多种影响,这意味着细胞内信号级联反应具有特异性。本文讨论了几种平行信号级联反应的作用,旨在确定这些靶点在调节运动介导的代谢和基因表达反应中的生理作用。