Maeba R, Ueta N
Department of Biochemistry, Teikyo University School of Medicine, Itabashi-Ku, Tokyo 173-8605, Japan.
Biochem Soc Trans. 2004 Feb;32(Pt 1):141-3. doi: 10.1042/bst0320141.
We have demonstrated a novel antioxidant action of ethanolamine plasmalogens both in protecting cholesterol from oxidation by free radicals and in lowering the oxidizability of membranes, along with the action of scavenging radicals, by the oxygen-uptake method using large unilamellar vesicles and the water-soluble azo-radical initiator, AAPH [2,2'-azobis-(2-amidino-propane) dihydrochloride].
我们已经证明了乙醇胺缩醛磷脂具有一种新的抗氧化作用,它既能保护胆固醇免受自由基氧化,又能降低膜的氧化能力,同时还具有清除自由基的作用。这是通过使用大单层囊泡和水溶性偶氮自由基引发剂AAPH [2,2'-偶氮双-(2-脒基丙烷)二盐酸盐] 的吸氧法来实现的。