Marks James G, Belsito Donald V, DeLeo Vincent A, Fowler Joseph F, Fransway Anthony F, Maibach Howard I, Mathias C G Toby, Pratt Melanie D, Rietschel Robert L, Sherertz Elizabeth F, Storrs Frances J, Taylor James S
Department of Dermatology, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Am J Contact Dermat. 2003 Jun;14(2):59-62.
Patch testing is the most worthwhile diagnostic tool for the evaluation of patients with suspected allergic contact dermatitis.
This study reports patch-testing results from July 1, 1998, to December 31, 2000, by the North American Contact Dermatitis Group.
Patients were tested with the same screening series of allergens, using a standardized patch-testing technique. The data from these patients were recorded on a standard computer entry form and analyzed.
Fifty allergens were tested on over 5,800 patients. Amidoamine, benzophenone-3, and iodopropynyl butylcarbamate were the new allergens. The top 10 allergens in frequency of positive reactions were identical to those of our 1996-to 1998-study period. The incidence of allergic nickel reactions continues to go up, leading all the test substances by 16.2%.
Our findings reinforce the need for a more comprehensive group of diagnostic allergens than is found in the T.R.U.E. TEST, which is sold in the United States.
斑贴试验是评估疑似过敏性接触性皮炎患者最有价值的诊断工具。
本研究报告北美接触性皮炎小组1998年7月1日至2000年12月31日的斑贴试验结果。
采用标准化斑贴试验技术，用相同的过敏原筛查系列对患者进行检测。这些患者的数据记录在标准计算机录入表格上并进行分析。
对5800多名患者检测了50种过敏原。酰胺胺、二苯甲酮-3和碘丙炔醇丁基氨甲酸酯是新的过敏原。阳性反应频率最高的前10种过敏原与我们1996年至1998年研究期间的相同。过敏性镍反应的发生率持续上升，比所有测试物质高出16.2%。
我们的研究结果强化了这样一种需求，即需要一组比在美国销售的TRUE TEST中包含的更全面的诊断过敏原。
