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牙科材料的过敏反应——一项系统评价

Allergic Reactions to Dental Materials-A Systematic Review.

作者信息

Syed Meena, Chopra Radhika, Sachdev Vinod

机构信息

Post Graduate Student, Department of Pedodontics, ITS-CDSR Centre for Dental studies and Research , Muradnagar, Ghaziabad, Uttar Pradesh, India .

Associate Professor, Department of Pedodontics and Preventive Dentistry, ITS-CDSR Centre for Dental studies and Research , Muradnagar, Ghaziabad, Uttar Pradesh, India .

出版信息

J Clin Diagn Res. 2015 Oct;9(10):ZE04-9. doi: 10.7860/JCDR/2015/15640.6589. Epub 2015 Oct 1.

Abstract

INTRODUCTION

Utility of various dental materials ranging from diagnosis to rehabilitation for the management of oral diseases are not devoid of posing a potential risk of inducing allergic reactions to the patient, technician and dentist. This review aims to develop a systematic approach for the selection and monitoring of dental materials available in the market thereby giving an insight to predict their risk of inducing allergic reactions.

MATERIALS AND METHODS

Our data included 71 relevant articles which included 60 case reports, 8 prospective studies and 3 retrospective studies. The source of these articles was Pub Med search done with the following terms: allergies to impression materials, sodium hypochlorite, Ledermix paste, zinc oxide eugenol, formaldehyde, Latex gloves, Methyl methacrylate, fissure sealant, composites, mercury, Nickel-chromium, Titanium, polishing paste and local anaesthesia. All the relevant articles and their references were analysed. The clinical manifestations of allergy to different dental materials based on different case reports were reviewed.

RESULTS

After reviewing the literature, we found that the dental material reported to cause most adverse reactions in patients is amalgam and the incidence of oral lichenoid reactions adjacent to amalgam restorations occur more often than other dental materials.

CONCLUSION

The most common allergic reactions in dental staff are allergies to latex, acrylates and formaldehyde. While polymethylmethacrylates and latex trigger delayed hypersensitivity reactions, sodium metabisulphite and nickel cause immediate reactions. Over the last few years, due to the rise in number of patients with allergies from different materials, the practicing dentists should have knowledge about documented allergies to known materials and thus avoid such allergic manifestations in the dental clinic.

摘要

引言

从口腔疾病的诊断到修复所使用的各种牙科材料,在对患者、技师和牙医引发过敏反应方面并非没有潜在风险。本综述旨在开发一种系统方法,用于市场上牙科材料的选择和监测,从而深入了解预测其引发过敏反应的风险。

材料与方法

我们的数据包括71篇相关文章,其中包括60篇病例报告、8篇前瞻性研究和3篇回顾性研究。这些文章的来源是通过以下关键词在PubMed上进行的搜索:印模材料过敏、次氯酸钠、Ledermix糊剂、氧化锌丁香酚、甲醛、乳胶手套、甲基丙烯酸甲酯、窝沟封闭剂、复合材料、汞、镍铬合金、钛、抛光膏和局部麻醉。对所有相关文章及其参考文献进行了分析。基于不同病例报告,对不同牙科材料过敏的临床表现进行了综述。

结果

在回顾文献后,我们发现据报道在患者中引起最多不良反应的牙科材料是汞合金,与汞合金修复体相邻的口腔苔藓样反应的发生率比其他牙科材料更高。

结论

牙科工作人员中最常见的过敏反应是对乳胶、丙烯酸酯和甲醛过敏。虽然聚甲基丙烯酸甲酯和乳胶引发迟发型超敏反应,但焦亚硫酸钠和镍会引起速发型反应。在过去几年中,由于对不同材料过敏的患者数量增加,执业牙医应该了解已知材料的已记录过敏情况,从而在牙科诊所避免此类过敏表现。

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