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机械环境和植入物设计对骨组织分化的作用:当前认知与未来展望

Role of mechanical environment and implant design on bone tissue differentiation: current knowledge and future contexts.

作者信息

Cehreli Murat, Sahin Saime, Akça Kivanç

机构信息

Department of Prosthodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.

出版信息

J Dent. 2004 Feb;32(2):123-32. doi: 10.1016/j.jdent.2003.09.003.

DOI:10.1016/j.jdent.2003.09.003
PMID:14749084
Abstract

OBJECTIVES

To evaluate published evidence related to bone reactions to varying loading regimens and the impact of implant design on bone tissue differentiation.

DATA AND SOURCES

The literature was searched for original research articles relating effect of mechanical environment on bone tissue and effects of implant design on bone biomechanics and marginal bone reactions using MEDLINE and manual tracing of references cited in key papers otherwise not elicited.

STUDY SELECTION

Current literature on biomechanics of bone and dental implants as main focus and pertinent to key aspects of the review.

CONCLUSIONS

Implant design influences force transmission characteristics in peri-implant bone, but not the time-dependent marginal bone reactions. Mechanical signals affect bone tissue differentiation. Therefore, it is essential to control biomechanical loads on implants to maintain osseointegration and/or to promote early bone-implant interface healing.

摘要

目的

评估已发表的有关不同加载方案对骨反应以及种植体设计对骨组织分化影响的证据。

数据与来源

使用MEDLINE检索关于机械环境对骨组织的影响以及种植体设计对骨生物力学和边缘骨反应的影响的原始研究文章,并手动追踪关键论文中引用的参考文献,否则无法获取。

研究选择

以骨和牙种植体生物力学的当前文献为主要重点,且与综述的关键方面相关。

结论

种植体设计会影响种植体周围骨中的力传递特性,但不会影响随时间变化的边缘骨反应。机械信号会影响骨组织分化。因此,控制种植体上的生物力学负荷对于维持骨结合和/或促进早期骨-种植体界面愈合至关重要。

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