Monro J A
New Zealand Institute for Crop and Food Research Limited, Palmerston North, New Zealand.
Eur J Clin Nutr. 2004 Feb;58(2):219-30. doi: 10.1038/sj.ejcn.1601769.
The ability to communicate food benefits is essential for the successful development of functional foods and their role in improving public health. However, the functional efficacy of foods often cannot be represented by food composition. The concept of virtual food components (VFCs)-food data that express health-related effects, properties or functions of foods in the format of food components-is therefore proposed.
To develop protocols for designing VFC data sets that communicate functional efficacies of foods to end users, in order to facilitate evidence-based food choice, and allow data management systems to provide a more complete description of nutritional effects of foods than has been possible with values for actual food components alone.
A framework within which to develop VFCs was constructed, linking food choice to health end points. It involves scientific validation, generation of relative indices, their translation into a meaningful language based on equivalents to known and understood reference foods, followed by data consolidation and ecological validation. Criteria used to evaluate VFCs were importance, independence, validity, accuracy, robustness, sensitivity, linearity/additivity, relevance, comprehensiveness, acquirability, completeness, meaningfulness, acceptability and safety. The developmental framework and evaluative criteria were applied to glycaemic glucose equivalents (GGE), a VFC representing postprandial glycaemia, and to wheat bran equivalents for faecal bulk (WBE(fb)), a VFC representing faecal bulking efficacy.
VFCs were used to identify foods according to health-related effects that cannot be accurately predicted from food composition data, and were used in a nutrition management system to concurrently show nutrient intake and physiological effects in the same units. The proposed evaluative criteria identified points requiring further research, and showed that lack of integrity-tested VFC data is an immediate challenge.
VFCs are a means of communicating relative functional efficacy of foods as a continuous variable, and provide end users with a more accurate and complete view of the health effects of foods than can be provided by health claims or food composition data alone.
传达食品益处的能力对于功能性食品的成功开发及其在改善公众健康方面的作用至关重要。然而,食品的功能功效往往无法通过食品成分来体现。因此,提出了虚拟食品成分(VFCs)的概念——即以食品成分形式表达食品与健康相关的效应、特性或功能的食品数据。
制定设计VFC数据集的方案,以便向终端用户传达食品的功能功效,从而促进基于证据的食品选择,并使数据管理系统能够比仅使用实际食品成分值更全面地描述食品的营养效应。
构建了一个开发VFCs的框架,将食品选择与健康终点联系起来。这包括科学验证、生成相对指数,将其转化为基于与已知且易懂的参考食品等效物的有意义语言,随后进行数据整合和生态验证。用于评估VFCs的标准包括重要性、独立性、有效性、准确性、稳健性、敏感性、线性/加和性、相关性、全面性、可获取性、完整性、意义性、可接受性和安全性。将该开发框架和评估标准应用于血糖葡萄糖当量(GGE),一种代表餐后血糖的VFC,以及用于粪便体积的麦麸当量(WBE(fb)),一种代表粪便膨松功效的VFC。
VFCs用于根据无法从食品成分数据准确预测的与健康相关的效应来识别食品,并用于营养管理系统中,以相同单位同时显示营养摄入和生理效应。所提出的评估标准确定了需要进一步研究的要点,并表明缺乏经过完整性测试的VFC数据是一个紧迫的挑战。
VFCs是一种将食品的相对功能功效作为连续变量进行传达的手段,与仅通过健康声明或食品成分数据相比,能为终端用户提供更准确、更全面的食品健康效应视图。