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[脊髓麻醉下剖宫产术后脑出血。是巧合还是因果关系?]

[Intracerebral hemorrhage after cesarean section under spinal anesthesia. Coincidence or causality?].

作者信息

von Knobelsdorff G, Paris A

机构信息

Klinik für Anästhesie, Intensivmedizin und Schmerztherapie, St. Bernward Krankenhaus, Hildesheim.

出版信息

Anaesthesist. 2004 Jan;53(1):41-4. doi: 10.1007/s00101-003-0585-9.

DOI:10.1007/s00101-003-0585-9
PMID:14749875
Abstract

Intracerebral haemorrhage is a rare complication of spinal anaesthesia in obstetrics. A 37-year-old woman without any accompanying disease during a twin pregnancy, underwent an urgent caesarean section due to insufficiency of the placenta under spinal anaesthesia using hyperbaric bupivacain (0.5%) and a pencil-point spinal needle Sprotte 27 Gauge. The patient developed severe headache, a hemiparesis of the right upper limb and became somnolent and finally unconscious 80 min after the procedure. An immediately performed computed tomographic scan revealed a large acute intracerebral haemorrhage in the left hemisphere region with mass effect. The patient underwent temporoparietal craniotomy. No obvious cause of the haemorrhage, such as aneurysm or arteriovenous malformation was found. The patient fully recovered and was weaned from the respirator 32 h postoperatively. On postoperative day 7 the remaining neurologic deficits included aphasis and severe hemiparesis of the right upper limb and a right extensor plantar response. The neurologic status did not improve substantially until 6 months after the complication. The case and the recent literature are discussed.

摘要

颅内出血是产科脊髓麻醉的一种罕见并发症。一名37岁双胎妊娠女性,无任何伴随疾病,因胎盘功能不全在脊髓麻醉下使用重比重布比卡因(0.5%)和27G笔尖式Sprotte脊髓穿刺针行急诊剖宫产术。术后80分钟,患者出现严重头痛、右上肢偏瘫,继而嗜睡,最终昏迷。立即进行的计算机断层扫描显示左半球区域有一大块急性颅内出血并伴有占位效应。患者接受了颞顶开颅手术。未发现明显的出血原因,如动脉瘤或动静脉畸形。患者术后32小时完全康复并脱机。术后第7天,残留的神经功能缺损包括失语、右上肢严重偏瘫和右侧跖伸反应。直到并发症发生6个月后,神经功能状态才基本改善。本文讨论了该病例及近期文献。

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Intracranial hematoma and abscess after neuraxial analgesia and anesthesia: a review of the literature describing 297 cases.椎管内镇痛和麻醉后颅内血肿及脓肿:对描述297例病例的文献综述
Reg Anesth Pain Med. 2021 Apr;46(4):337-343. doi: 10.1136/rapm-2020-102154. Epub 2021 Jan 13.

本文引用的文献

1
Spontaneous intracerebral hemorrhage: epidemiology and clinical presentation.自发性脑出血:流行病学与临床表现
Neurosurg Clin N Am. 2002 Jul;13(3):265-79, v. doi: 10.1016/s1042-3680(02)00011-6.
2
Maternal deaths from anaesthesia. An extract from Why mothers die 1997-1999, the Confidential Enquiries into Maternal Deaths in the United Kingdom.麻醉导致的孕产妇死亡。摘自《1997 - 1999年英国孕产妇死亡秘密调查报告:为何母亲会死亡》。
Br J Anaesth. 2002 Sep;89(3):499-508.
3
Intracerebral hemorrhage after spinal anesthesia.脊髓麻醉后脑出血
J Neurosurg Anesthesiol. 2002 Jul;14(3):234-7. doi: 10.1097/00008506-200207000-00011.
4
Subdural hygroma: a rare complication of spinal anesthesia.硬膜下积液:脊髓麻醉的一种罕见并发症。
Anesth Analg. 2002 Jun;94(6):1625-7, table of contents. doi: 10.1097/00000539-200206000-00049.
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Bilateral frontal haemorrhages associated with continuous spinal analgesia.与连续脊髓镇痛相关的双侧额叶出血。
Anaesth Intensive Care. 2001 Feb;29(1):51-3. doi: 10.1177/0310057X0102900110.
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Intracranial haemorrhage following lumbar myelography: case report and review of the literature.
Neuroradiology. 2000 Mar;42(3):211-4. doi: 10.1007/s002340050049.
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Serious complications related to regional anesthesia: results of a prospective survey in France.与区域麻醉相关的严重并发症:法国一项前瞻性调查的结果
Anesthesiology. 1997 Sep;87(3):479-86. doi: 10.1097/00000542-199709000-00005.
9
Postdural puncture headache and spinal needle design. Metaanalyses.硬膜穿刺后头痛与脊髓穿刺针设计。荟萃分析。
Anesthesiology. 1994 Dec;81(6):1376-83. doi: 10.1097/00000542-199412000-00012.
10
Clinical report of the occurrence of an intracerebral hemorrhage following post-lumbar puncture headache.
Anesthesiology. 1981 Dec;55(6):684-5. doi: 10.1097/00000542-198155060-00014.