De Celis José F, Diaz-Benjumea Fernando J
Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid, Spain.
Int J Dev Biol. 2003;47(7-8):653-63.
The venation patterns characteristics of different insect orders and of families belonging to the same order possess enormous variation in vein number, position and differentiation. Although the developmental basis of changes in vein patterns during evolution is entirely unknown, the identification of the genes and developmental processes involved in Drosophila vein pattern formation facilitates the elaboration of construction rules. It is thus possible to identify the likely changes which may constitute a source of pattern variation during evolution. In this review, we discuss how actual patterns of venation could be accounted for by modifications in different Pterygota of a common set of developmental operations. We argue that the individual specification of each vein and the modular structure of the regulatory regions of the key genes identified in Drosophila offer candidate entry points for pattern modifications affecting individual veins or interveins independently. Assuming a general conservation of the processes involved in different species, the transitions between different patterns may require few changes in the regulatory gene networks involved.
不同昆虫目以及同一目内不同科的脉序模式在翅脉数量、位置和分化方面存在巨大差异。尽管进化过程中翅脉模式变化的发育基础完全未知，但对果蝇翅脉模式形成所涉及的基因和发育过程的鉴定有助于阐明构建规则。因此，有可能识别出那些可能构成进化过程中模式变异来源的潜在变化。在本综述中，我们讨论了如何通过对一组共同发育操作在不同有翅亚纲昆虫中的修饰来解释实际的脉序模式。我们认为，果蝇中鉴定出的每个翅脉的个体特化以及关键基因调控区域的模块化结构为独立影响单个翅脉或翅脉间区域的模式修饰提供了候选切入点。假设不同物种所涉及的过程具有普遍保守性，那么不同模式之间的转变可能仅需要涉及的调控基因网络发生很少的变化。
