Wang C X, Zhou X, Wang M
School of Mechanical and Production Engineering, Nanyang Technological University, Nanyang Avenue, Singapore 639798, Singapore.
Biomed Mater Eng. 2004;14(1):5-11.
The mechanism of bone-like apatite formation on the surface of pure titanium pretreated with NaOH solution is still being investigated. The apatite formation may depend on the solution that is used. In the present study, several types of solutions such as simulated body fluid (SBF), calcium aqueous solution (CAS), and phosphate aqueous solution (PAS) were used to investigate bone-like apatite formation on alkali-treated titanium. In order to observe the effect of hydrolysis on the apatite formation, experiments of pretreated titanium immersed in distilled water before the immersion in SBF were also conducted. The results showed that the mechanism of apatite formation was the hydrolysis reaction of sodium titanate which induced the apatite formation. The pre-precipitation of either calcium or phosphate could prevent the apatite formation on the surface of alkaline treated titanium.
用氢氧化钠溶液预处理的纯钛表面骨样磷灰石形成的机制仍在研究中。磷灰石的形成可能取决于所使用的溶液。在本研究中，使用了几种类型的溶液，如模拟体液（SBF）、钙水溶液（CAS）和磷酸盐水溶液（PAS），来研究碱处理钛表面骨样磷灰石的形成。为了观察水解对磷灰石形成的影响，还进行了预处理钛在浸入SBF之前先浸入蒸馏水中的实验。结果表明，磷灰石形成的机制是钛酸钠的水解反应诱导了磷灰石的形成。钙或磷酸盐的预沉淀可以防止碱处理钛表面的磷灰石形成。
