To Teresa, Vydykhan Tatiana N, Dell Sharon, Tassoudji Marjan, Harris Jennifer K
Population Health Sciences, Research Institute, and the Division of Respiratory Medicine, Hospital for Sick Children, Toronto, Ontario, Canada.
J Pediatr. 2004 Feb;144(2):162-8. doi: 10.1016/j.jpeds.2003.09.047.
The aim of this study was to evaluate the association between obesity and asthma in a population-based sample of Canadian children.
Baseline data from the National Longitudinal Survey of Children and Youth were used in this cross-sectional study. We included 11199 children age 4 to 11 years whose biological mother reported data on asthma, height, and weight. Body mass index was categorized, and obesity was defined as body mass index >or=85th percentile. Children with asthma had parents who reported the diagnosis, and they took prescribed inhalants, had wheezing or an attack in the previous year, or had their activities limited by asthma. Multiple logistic regression was used.
The prevalence of asthma was 9.9%. Maternal history of asthma was a risk factor for asthma among all children. Single child status and maternal depression were risk factors for girls. The odds ratio for asthma, comparing highest and lowest body mass index categories, was 1.02 (99% confidence interval, 0.70-1.46) for boys and 1.06 (99% confidence interval, 0.67-1.69) for girls.
This study suggests that there is no statistical association between obesity and asthma among Canadian children age 4 to 11 years.
本研究旨在评估加拿大儿童人群样本中肥胖与哮喘之间的关联。
本横断面研究使用了儿童与青少年全国纵向调查的基线数据。我们纳入了11199名4至11岁的儿童，其亲生母亲报告了有关哮喘、身高和体重的数据。对体重指数进行分类，肥胖定义为体重指数≥第85百分位数。患有哮喘的儿童其父母报告了诊断情况，并且他们服用了处方吸入剂，在前一年有喘息或发作，或者其活动受到哮喘限制。使用了多元逻辑回归分析。
哮喘患病率为9.9%。母亲有哮喘病史是所有儿童患哮喘的一个危险因素。独生子女身份和母亲抑郁是女孩患哮喘的危险因素。比较最高和最低体重指数类别，男孩哮喘的优势比为1.02（99%置信区间，0.70 - 1.46），女孩为1.06（99%置信区间，0.67 - 1.69）。
本研究表明，4至11岁的加拿大儿童中肥胖与哮喘之间不存在统计学关联。
