Kaye J A, Jick H
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, 11 Muzzey Street, Lexington, MA 02421, USA.
Br J Cancer. 2004 Feb 9;90(3):635-7. doi: 10.1038/sj.bjc.6601566.
In a matched case-control study using the General Practice Research Database, current statin use was not associated with a significantly altered risk of any of 13 studied cancers. Untreated hyperlipidaemia was associated with slightly increased risks of colon cancer (relative risk 1.8; 95% confidence interval 1.2-2.8), prostate cancer (1.5; 1.1-2.0), and bladder cancer (1.9; 1.2-3.1).
在一项利用全科医疗研究数据库开展的配对病例对照研究中，当前使用他汀类药物与所研究的13种癌症中任何一种的风险显著改变均无关联。未经治疗的高脂血症与结肠癌（相对风险1.8；95%置信区间1.2 - 2.8）、前列腺癌（1.5；1.1 - 2.0）和膀胱癌（1.9；1.2 - 3.1）的风险略有增加相关。
