Aoki T, Kojima M, Adachi J, Okano M
Department of Dermatology, Habikino Hospital, Osaka, Japan.
Acta Derm Venereol Suppl (Stockh). 1992;176:99-102.
A unique, single-blind, controlled trial of egg exclusion was performed in infants under 3 years of age, with atopic dermatitis, and/or their breast-feeding mothers. All subjects were put on an exclusion diet, but assessment of the effect of egg exclusion was made without knowing the results of allergy the tests. Results showed that there was a statistically significant correlation between the effect of egg exclusion and egg allergy, but only in infants 3-6 months old. Combination with other allergies did not seem to affect the results at this age. These findings indicate that egg exclusion is effective in ameliorating skin symptoms of atopic dermatitis only in early infancy and in the presence of egg allergy, irrespective of combination with other food allergies. This may be correlated to high RAST scores to egg at this age.
对3岁以下患有特应性皮炎的婴儿和/或其母乳喂养的母亲进行了一项独特的单盲对照鸡蛋排除试验。所有受试者都采用排除饮食，但在不知道过敏测试结果的情况下评估鸡蛋排除的效果。结果显示，鸡蛋排除效果与鸡蛋过敏之间存在统计学上的显著相关性，但仅在3至6个月大的婴儿中如此。在这个年龄段，与其他过敏合并似乎并不影响结果。这些发现表明，仅在婴儿早期且存在鸡蛋过敏的情况下，排除鸡蛋对改善特应性皮炎的皮肤症状有效，无论是否与其他食物过敏合并。这可能与这个年龄段对鸡蛋的高RAST评分相关。
