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牛奶和/或鸡蛋无敏饮食对特应性皮炎患儿的影响

Results of a milk and/or egg free diet in children with atopic dermatitis.

作者信息

Businco L, Businco E, Cantani A, Galli E, Infussi R, Benincori N

出版信息

Allergol Immunopathol (Madr). 1982 Jul-Aug;10(4):283-8.

PMID:7180794
Abstract

Food allergy plays an important role in the pathogenesis of atopic dermatitis. Exclusion of eggs and milk from the diet of children during the first few months of life has been proven to significantly reduce the severity of eczema in children aged between 2 and 8 years. We studied the efficacy of exclusion of milk and/or egg from the diet of 59 children with severe atopic dermatitis. A detailed personal and family history was obtained. Total and specific IgE levels were determined on one hand, and intracutaneous tests were evaluated on the other. All allergens suspected of being implicated in the genesis of atopic dermatitis were eliminated from the diet. Clinical improvement was observed in 80% of cases after dietary exclusion. The younger children responded best, and the response to diet was not influenced by the severity of the eczema. No relation was observed between the family history of atopy and response to diet. Neither total nor specific IgE titers presented significant differences when the responder groups were compared.

摘要

食物过敏在特应性皮炎的发病机制中起重要作用。已证实,在生命的最初几个月从儿童饮食中排除鸡蛋和牛奶,可显著降低2至8岁儿童湿疹的严重程度。我们研究了从59例重度特应性皮炎患儿的饮食中排除牛奶和/或鸡蛋的效果。获取了详细的个人和家族病史。一方面测定了总IgE和特异性IgE水平,另一方面评估了皮内试验。从饮食中消除了所有怀疑与特应性皮炎发病有关的过敏原。饮食排除后80%的病例观察到临床改善。年龄较小的儿童反应最佳,对饮食的反应不受湿疹严重程度的影响。未观察到特应性家族史与饮食反应之间的关系。比较反应组时,总IgE和特异性IgE滴度均未呈现显著差异。

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