de Almeida Cláudia Angela Vilela, Lins Otávio Gomes, Lins Salustiano Gomes, Laurentino Sílvia, Valença Marcelo Moraes
Servi o de Neurologia e Neurocirurgia, Departamento de Neuropsiquiatria, Hospital das Clínicas, Universidade Federal de Pernambuco, Recife PE, Brasil.
Arq Neuropsiquiatr. 2003 Dec;61(4):979-87. doi: 10.1590/s0004-282x2003000600017. Epub 2004 Jan 6.
The objective of this study was to evaluate sleep macrostructure and sleep disturbance in a group of 39 patients with temporal lobe epilepsy (TLE). Patients completed questionnaires to evaluate their sleep and subjective daytime sleepiness (Epworth Sleepiness Scale [ESS]) and undergone Polysomnography and Multiple Sleep Latency Test (MSLT). Daytime sleepiness was the most frequent complaint (85%), followed by wakefulness during sleep, history of seizures during sleep (75%) and initial insomnia (26%). Parasomnias (67%), obstructive sleep apneas (13%), restless legs syndrome (15%) and periodic limb movements (5%) were the most frequent sleep disorders. The most frequent changes of sleep patterns were: sleep architecture fragmentation (100%), decreased amount of REM sleep (92%) and increase in time awake after sleep onset (77%). There were significative correlations between the ESS and the MSLT (p<0,05). In conclusion, TLE patients have fragmented sleep with increased sleep stages shifts, increased number of awakenings and in time awake after sleep onset. REM sleep was decreased. Daytime sleepiness was the most frequent complaint in TLE patients.
本研究的目的是评估39例颞叶癫痫（TLE）患者的睡眠宏观结构和睡眠障碍。患者完成问卷以评估其睡眠情况和主观日间嗜睡程度（爱泼沃斯嗜睡量表[ESS]），并接受多导睡眠图和多次睡眠潜伏期试验（MSLT）。日间嗜睡是最常见的主诉（85%），其次是睡眠中觉醒、睡眠中癫痫发作史（75%）和初始失眠（26%）。异态睡眠（67%）、阻塞性睡眠呼吸暂停（13%）、不宁腿综合征（15%）和周期性肢体运动（5%）是最常见的睡眠障碍。最常见的睡眠模式变化为：睡眠结构碎片化（100%）、快速眼动睡眠量减少（92%）和睡眠开始后清醒时间增加（77%）。ESS与MSLT之间存在显著相关性（p<0.05）。总之，TLE患者睡眠碎片化，睡眠阶段转换增加，觉醒次数增加，睡眠开始后清醒时间增加。快速眼动睡眠减少。日间嗜睡是TLE患者最常见的主诉。
