Martinez S A, Probst C W, Hauptman J G, Weisbrode S E
Department of Small Animal Clinical Sciences, Veterinary Medical Center, Michigan State University, East Lansing 48824-1314.
Am J Vet Res. 1992 Dec;53(12):2381-5.
A standardized cortical defect was created on the caudal cortex of the proximal portion of each ulna in 5 adult mixed-breed dogs. One gram of autogenous cancellous bone graft (ACBG) was obtained from the greater tubercle of the ipsilateral humerus. The cortical defect in the ulna of 1 limb was filled with 1 g of ACBG that had been compressed with 2-MPa pressure for 30 seconds. One gram of noncompressed ACBG was placed into the contralateral ulnar cortical defect. The compressed and noncompressed ACBG recipient sites were radiographed at weekly intervals. Dogs were euthanatized 8 weeks after surgery, and the ACBG recipient sites were harvested for histomorphometric analysis. Optical densitometry was performed on all radiographs. There was no significant difference between compressed and noncompressed ACBG with optical densitometry or histomorphometric analysis for total bone area. We concluded that there was no difference in osteogenic capability between compressed and noncompressed ACBG of equal mass.
在5只成年杂种犬的每只尺骨近端的尾侧皮质上制造一个标准化的皮质缺损。从同侧肱骨的大结节获取1克自体松质骨移植（ACBG）。将1克经2兆帕压力压缩30秒的ACBG填充到1只肢体尺骨的皮质缺损处。将1克未压缩的ACBG放入对侧尺骨皮质缺损处。对压缩和未压缩ACBG的接受部位每周进行一次X光检查。术后8周对犬实施安乐死，并获取ACBG接受部位进行组织形态计量分析。对所有X光片进行光密度测定。在光密度测定或组织形态计量分析的总骨面积方面，压缩和未压缩的ACBG之间没有显著差异。我们得出结论，等质量的压缩和未压缩ACBG在成骨能力上没有差异。
