Watson J Tracy
Department of Orthopedic Surgery, St Louis University School of Medicine, St Louis, Mo, USA.
Orthopedics. 2004 Jan;27(1 Suppl):s103-7. doi: 10.3928/0147-7447-20040102-04.
Eight consecutive patients with severely comminuted proximal or distal tibial metaphyseal fractures were surgically treated with a novel injectable, in situ hardening calcium sulfate material to provide temporary intraoperative structural support until instrumentation was appropriately placed. The calcium sulfate bone substitute was also used as a bone void filler to provide an osteoconductive environment following stabilization. Bone regrowth was observed in all patients and, in seven of the eight patients, 90%-100% bone formation was observed within 3 months. The bone substitute had almost completely resorbed by 3 months in all patients. One patient with extensive initial bone loss required a second bone graft. Although the patient sample size was small, the success rate of treating severely comminuted fractures was significantly better than in reports using only internal fixation. Injectable bone substitute for minimally invasive surgery to repair metaphyseal fractures.
连续8例胫骨近端或远端严重粉碎性干骺端骨折患者接受了一种新型可注射原位硬化硫酸钙材料的手术治疗，以在适当放置内固定器械之前提供临时术中结构支撑。硫酸钙骨替代物还用作骨缺损填充剂，以在稳定后提供骨传导环境。所有患者均观察到骨再生，8例患者中有7例在3个月内观察到90%-100%的骨形成。所有患者的骨替代物在3个月时几乎完全吸收。1例初始骨丢失广泛的患者需要再次植骨。尽管患者样本量较小，但治疗严重粉碎性骨折的成功率明显优于仅使用内固定的报告。用于微创手术修复干骺端骨折的可注射骨替代物。
