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糖尿病患者的支架再狭窄及药物洗脱支架的应用

Stent restenosis and the use of drug-eluting stents in patients with diabetes mellitus.

作者信息

Sarembock Ian J

机构信息

Cardiovascular Division and Cardiovascular Research Center, University of Virginia Health System, Box 800158, Charlottesville, VA 22908-0158, USA.

出版信息

Curr Diab Rep. 2004 Feb;4(1):13-9. doi: 10.1007/s11892-004-0005-9.

DOI:10.1007/s11892-004-0005-9
PMID:14764274
Abstract

Stents have become the technique of choice for percutaneous revascularization, but in-stent restenosis has remained a clinical challenge. This brief article summarizes the incidence, patterns, and proposed mechanisms of restenosis and outlines its contemporary management with specific focus on the diabetic patient. It includes a synopsis of the strategy of drug-eluting stents, which is the most recent and major advance in percutaneous coronary intervention.

摘要

支架已成为经皮血管重建的首选技术,但支架内再狭窄仍然是一项临床挑战。这篇短文总结了再狭窄的发生率、模式及推测机制,并概述了其现代治疗方法,特别关注糖尿病患者。文中还简要介绍了药物洗脱支架策略,这是经皮冠状动脉介入治疗领域最新且最重大的进展。

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Stent restenosis and the use of drug-eluting stents in patients with diabetes mellitus.糖尿病患者的支架再狭窄及药物洗脱支架的应用
Curr Diab Rep. 2004 Feb;4(1):13-9. doi: 10.1007/s11892-004-0005-9.
2
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引用本文的文献

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Clinical impact of drug-eluting stents in an unselected population of diabetic patients.药物洗脱支架在未选择的糖尿病患者人群中的临床影响。
Clin Cardiol. 2008 Apr;31(4):165-71. doi: 10.1002/clc.20182.

本文引用的文献

1
Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.雷帕霉素洗脱支架与标准支架治疗冠状动脉狭窄患者的比较
N Engl J Med. 2003 Oct 2;349(14):1315-23. doi: 10.1056/NEJMoa035071.
2
TRANSLUMINAL TREATMENT OF ARTERIOSCLEROTIC OBSTRUCTION. DESCRIPTION OF A NEW TECHNIC AND A PRELIMINARY REPORT OF ITS APPLICATION.动脉粥样硬化性梗阻的腔内治疗。一种新技术的描述及其应用的初步报告。
Circulation. 1964 Nov;30:654-70. doi: 10.1161/01.cir.30.5.654.
3
Randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for coronary artery lesions.
评估基于聚合物的缓释和中释紫杉醇洗脱支架治疗冠状动脉病变有效性的随机研究。
Circulation. 2003 Aug 19;108(7):788-94. doi: 10.1161/01.CIR.0000086926.62288.A6. Epub 2003 Aug 4.
4
Impact of restenosis and disease progression on clinical outcome after multivessel stenting in diabetic patients.再狭窄和疾病进展对糖尿病患者多支血管支架置入术后临床结局的影响。
Catheter Cardiovasc Interv. 2003 Apr;58(4):451-4. doi: 10.1002/ccd.10455.
5
Percutaneous coronary intervention versus coronary bypass graft surgery for diabetic patients with unstable angina and risk factors for adverse outcomes with bypass: outcome of diabetic patients in the AWESOME randomized trial and registry.经皮冠状动脉介入治疗与冠状动脉搭桥手术治疗合并不稳定型心绞痛及搭桥不良预后危险因素的糖尿病患者:AWESOME随机试验及登记研究中糖尿病患者的结局
J Am Coll Cardiol. 2002 Nov 6;40(9):1555-66. doi: 10.1016/s0735-1097(02)02346-x.
6
Comparison of in-hospital and one-year outcomes in patients with and without diabetes mellitus undergoing percutaneous catheter intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry).
Am J Cardiol. 2002 Nov 15;90(10):1062-7. doi: 10.1016/s0002-9149(02)02770-4.
7
Persistent inhibition of neointimal hyperplasia after sirolimus-eluting stent implantation: long-term (up to 2 years) clinical, angiographic, and intravascular ultrasound follow-up.西罗莫司洗脱支架植入术后新内膜增生的持续抑制:长期(长达2年)临床、血管造影和血管内超声随访
Circulation. 2002 Sep 24;106(13):1610-3. doi: 10.1161/01.cir.0000034447.02535.d5.
8
Impact of different platelet glycoprotein IIb/IIIa receptor inhibitors among diabetic patients undergoing percutaneous coronary intervention: : Do Tirofiban and ReoPro Give Similar Efficacy Outcomes Trial (TARGET) 1-year follow-up.不同血小板糖蛋白IIb/IIIa受体抑制剂对接受经皮冠状动脉介入治疗的糖尿病患者的影响:替罗非班与瑞替普酶疗效相似性试验(TARGET)1年随访
Circulation. 2002 Jun 11;105(23):2730-6. doi: 10.1161/01.cir.0000018123.02672.c7.
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A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization.西罗莫司洗脱支架与标准支架用于冠状动脉血运重建的随机对照研究。
N Engl J Med. 2002 Jun 6;346(23):1773-80. doi: 10.1056/NEJMoa012843.
10
The impact of tranilast on restenosis after coronary angioplasty: the Second Tranilast Restenosis Following Angioplasty Trial (TREAT-2).曲尼司特对冠状动脉成形术后再狭窄的影响:第二项曲尼司特预防血管成形术后再狭窄试验(TREAT - 2)
Am Heart J. 2002 Mar;143(3):506-13. doi: 10.1067/mhj.2002.120770.