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糖尿病患者的支架再狭窄及药物洗脱支架的应用

Stent restenosis and the use of drug-eluting stents in patients with diabetes mellitus.

作者信息

Sarembock Ian J

机构信息

Cardiovascular Division and Cardiovascular Research Center, University of Virginia Health System, Box 800158, Charlottesville, VA 22908-0158, USA.

出版信息

Curr Diab Rep. 2004 Feb;4(1):13-9. doi: 10.1007/s11892-004-0005-9.

Abstract

Stents have become the technique of choice for percutaneous revascularization, but in-stent restenosis has remained a clinical challenge. This brief article summarizes the incidence, patterns, and proposed mechanisms of restenosis and outlines its contemporary management with specific focus on the diabetic patient. It includes a synopsis of the strategy of drug-eluting stents, which is the most recent and major advance in percutaneous coronary intervention.

摘要

支架已成为经皮血管重建的首选技术,但支架内再狭窄仍然是一项临床挑战。这篇短文总结了再狭窄的发生率、模式及推测机制,并概述了其现代治疗方法,特别关注糖尿病患者。文中还简要介绍了药物洗脱支架策略,这是经皮冠状动脉介入治疗领域最新且最重大的进展。

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