伴有凝血病的血管瘤：对泼尼松持续有效。

Evans J, Batchelor A D, Stark G, Uttley W S

Arch Dis Child. 1975 Oct;50(10):809-12. doi: 10.1136/adc.50.10.809.

Two cases of giant haemangioma with thrombocytopenia are described. A satisfactory and sustained response to prednisone was achieved in respect of both coagulation abnormalities and tumour size. It is proposed that prednisone is effective by enhancement of thrombosis and reduction of fibrinolysis within the tumour, thus promoting a natural form of resolution. It is suggested that prednisone therapy should be first-choice treatment of complicated haemangiomas.

本文描述了两例伴有血小板减少症的巨大血管瘤病例。泼尼松对凝血异常和肿瘤大小均取得了满意且持续的疗效。有人提出，泼尼松的作用机制是增强肿瘤内的血栓形成并减少纤维蛋白溶解，从而促进一种自然的消退形式。有人认为泼尼松疗法应作为复杂性血管瘤的首选治疗方法。