Channon Shelley, Crawford Sarah, Vakili Kian, Robertson Mary M
Department of Psychology, University College London, School of Medicine, London, UK.
Cogn Behav Neurol. 2003 Mar;16(1):3-15.
The main objective of the study was to examine social problem solving in real-life-type situations in Tourette syndrome (TS).
Studies of cognitive functioning in TS have usually focused on nonsocial, abstract tasks, with mixed findings as to whether there is evidence of impairment in executive functions in those without comorbid disorders. The current study focuses primarily on social functioning, using a problem-solving task known to be sensitive to frontal lobe lesions.
TS participants without comorbid diagnoses were compared with matched healthy control participants on a problem-solving task, using a range of interpersonal problem scenarios presented on video. A set of more abstract executive tests was also included.
Participants with TS were found to perform below a matched control group on the problem-solving task both in generating a range of potential problem solutions, and in selecting appropriate final solutions. They also performed more poorly on aspects of executive function.
This study provides evidence of difficulties in both social and nonsocial aspects of functioning in TS. The implications of the findings for our understanding of TS and problem solving are discussed.
本研究的主要目的是考察抽动秽语综合征（TS）患者在现实生活类型情境中的社会问题解决能力。
对TS患者认知功能的研究通常集中在非社会性、抽象任务上，对于那些没有共病障碍的患者是否存在执行功能受损的证据，研究结果不一。当前研究主要聚焦于社会功能，采用一项已知对额叶损伤敏感的问题解决任务。
将无共病诊断的TS参与者与匹配的健康对照参与者进行比较，让他们完成一项问题解决任务，该任务使用视频呈现一系列人际问题情境。还包括一组更抽象的执行测试。
发现在生成一系列潜在问题解决方案以及选择合适的最终解决方案方面，TS参与者在问题解决任务中的表现低于匹配的对照组。他们在执行功能方面的表现也更差。
本研究提供了TS患者在功能的社会和非社会方面均存在困难的证据。讨论了这些发现对我们理解TS和问题解决的意义。
