Barros Monica Bastos de Lima, Schubach Armando de Oliveira, do Valle Antônio Carlos Francesconi, Gutierrez Galhardo Maria Clara, Conceição-Silva Fátima, Schubach Tânia Maria Pacheco, Reis Rosani Santos, Wanke Bodo, Marzochi Keyla Belizia Feldman, Conceição Maria José
Servico de Infectologia, Instituto de Pesquisa Clinica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Manguinhos, Rio de Janeiro, Brazil.
Clin Infect Dis. 2004 Feb 15;38(4):529-35. doi: 10.1086/381200. Epub 2004 Jan 29.
Sporotrichosis is the most common subcutaneous mycosis in South America. Classic infection is associated with traumatic inoculation of soil, vegetables, and organic matter contaminated with Sporothrix schenckii. Zoonotic transmission has been described in isolated cases or in small outbreaks. Since 1998, we have been observing an increasing number of cases of sporotrichosis in persons from the city of Rio de Janeiro, Brazil, and surroundings. From 1998 to 2001, 178 cases of culture-proven sporotrichosis had been diagnosed. Female patients predominated, and the median age was 39 years. The most frequent clinical presentation was lymphocutaneous disease. Of the 178 patients, 156 reported domiciliary or professional contact with cats with sporotrichosis, and 97 of these patients had a history of receipt of cat scratch or bite. The patients received itraconazole as first-line treatment. This study suggests that feline transmission of sporotrichosis was associated with a large and long-lasting outbreak of the disease in Rio de Janeiro.
孢子丝菌病是南美洲最常见的皮下真菌病。典型感染与土壤、蔬菜以及被申克孢子丝菌污染的有机物的创伤性接种有关。人兽共患病传播在个别病例或小规模暴发中已有报道。自1998年以来，我们一直在观察巴西里约热内卢市及其周边地区孢子丝菌病病例数的增加。1998年至2001年，共诊断出178例经培养证实的孢子丝菌病病例。女性患者居多，中位年龄为39岁。最常见的临床表现是皮肤淋巴管型疾病。在这178例患者中，156例报告在家中或工作中接触过患有孢子丝菌病的猫，其中97例患者有被猫抓或咬的病史。患者接受伊曲康唑作为一线治疗。这项研究表明，里约热内卢孢子丝菌病的猫传感染与该病大规模、长期的暴发有关。
