Cohen I R
Dept of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Immunol Today. 1992 Nov;13(11):441-4. doi: 10.1016/0167-5699(92)90071-E.
Here, Irun Cohen argues that the clonal selection paradigm is no longer a convenient paradigm for organizing thinking about the immune system. He contends that most immunologists now investigate questions for which the clonal selection paradigm makes no provision and that one of its major tenets is contradicted by the prevalence of natural autoimmunity. Instead, he proposes a cognitive paradigm.
在此，伊伦·科恩认为克隆选择范式已不再是组织关于免疫系统思维的便利范式。他主张，如今大多数免疫学家所研究的问题，克隆选择范式并未涉及，而且其自然自身免疫的普遍存在与该范式的一个主要信条相矛盾。相反，他提出了一种认知范式。
