Heilman Kenneth M
Department of Neurology, L3-100 McKnight Brain Institute, University of Florida College of Medicine, Newell Drive, Gainesville, Florida 32610, USA.
Front Biosci. 2004 Jan 1;9:694-705. doi: 10.2741/1261.
The neglect syndrome has been defined as a failure to report, respond or orient to novel or meaningful stimuli presented to the side opposite of a brain lesion when this failure can not be attributed to elemental sensory (e.g., hemianopia) or motor (hemiplegia) deficits. This failure to report, respond or orient can be induced by attentional, representation-memory, and intentional deficits. The four major intentional deficits that can be associated with neglect include, akinesia (body part, directional and hemispatial), impersistence, defective response inhibition and motor perseveration. In this article we define and discuss each of these intentional disorders, describe how to test patients for these disorders and the neuropsychological and pathophysiological mechanisms that might be associated with these disorders.
当无法将对呈现于脑损伤对侧的新异或有意义刺激的报告、反应或定向缺失归因于基本感觉(如偏盲)或运动(偏瘫)缺陷时,出现的这种报告、反应或定向缺失。这种报告、反应或定向缺失可由注意力、表征记忆和意向缺陷诱发。与忽视相关的四种主要意向缺陷包括运动不能(身体部位、方向和半侧空间)、持续性障碍、反应抑制缺陷和运动持续性。在本文中,我们定义并讨论每种意向障碍,描述如何对患者进行这些障碍的测试,以及可能与这些障碍相关的神经心理学和病理生理学机制。