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在疑似患有念珠菌性脑膜炎患者的脑脊液标本中检测念珠菌抗原甘露聚糖。

Detection of the Candida antigen mannan in cerebrospinal fluid specimens from patients suspected of having Candida meningitis.

作者信息

Verduyn Lunel Frans M, Voss Andreas, Kuijper Ed J, Gelinck L B S, Hoogerbrugge Peter M, Liem K L, Kullberg Bart Jan, Verweij Paul E

机构信息

Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands.

出版信息

J Clin Microbiol. 2004 Feb;42(2):867-70. doi: 10.1128/JCM.42.2.867-870.2004.

DOI:10.1128/JCM.42.2.867-870.2004
PMID:14766875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC344464/
Abstract

Cerebrospinal fluid samples from five patients from which Candida cells were cultured were tested for the presence of mannan. Samples from four patients categorized as having proven candidosis reacted positively. Samples from the remaining patient and from patients with other central nervous system infections were negative. Detection of mannan may be valuable in the diagnosis of Candida meningitis.

摘要

对从五名培养出念珠菌细胞的患者采集的脑脊液样本进行了甘露聚糖检测。在被归类为确诊念珠菌病的四名患者的样本中检测呈阳性。其余一名患者以及患有其他中枢神经系统感染患者的样本检测呈阴性。甘露聚糖的检测在念珠菌性脑膜炎的诊断中可能具有重要价值。

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