在疑似患有念珠菌性脑膜炎患者的脑脊液标本中检测念珠菌抗原甘露聚糖。
Detection of the Candida antigen mannan in cerebrospinal fluid specimens from patients suspected of having Candida meningitis.
作者信息
Verduyn Lunel Frans M, Voss Andreas, Kuijper Ed J, Gelinck L B S, Hoogerbrugge Peter M, Liem K L, Kullberg Bart Jan, Verweij Paul E
机构信息
Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands.
出版信息
J Clin Microbiol. 2004 Feb;42(2):867-70. doi: 10.1128/JCM.42.2.867-870.2004.
Abstract
Cerebrospinal fluid samples from five patients from which Candida cells were cultured were tested for the presence of mannan. Samples from four patients categorized as having proven candidosis reacted positively. Samples from the remaining patient and from patients with other central nervous system infections were negative. Detection of mannan may be valuable in the diagnosis of Candida meningitis.
摘要
对从五名培养出念珠菌细胞的患者采集的脑脊液样本进行了甘露聚糖检测。在被归类为确诊念珠菌病的四名患者的样本中检测呈阳性。其余一名患者以及患有其他中枢神经系统感染患者的样本检测呈阴性。甘露聚糖的检测在念珠菌性脑膜炎的诊断中可能具有重要价值。
相似文献
1
Detection of the Candida antigen mannan in cerebrospinal fluid specimens from patients suspected of having Candida meningitis.在疑似患有念珠菌性脑膜炎患者的脑脊液标本中检测念珠菌抗原甘露聚糖。
J Clin Microbiol. 2004 Feb;42(2):867-70. doi: 10.1128/JCM.42.2.867-870.2004.
2
Culture-negative Candida meningitis diagnosed by detection of Candida mannan antigen in CSF.通过检测脑脊液中的念珠菌甘露聚糖抗原诊断出的培养阴性念珠菌性脑膜炎。
Neurology. 2013 Oct 22;81(17):1555-6. doi: 10.1212/WNL.0b013e3182a95871. Epub 2013 Sep 25.
3
Challenging diagnosis of chronic cerebral fungal infection: Value of (1→3)-ß-D-glucan and mannan antigen testing in cerebrospinal fluid and of cerebral ventricle puncture.慢性脑真菌性感染的诊断挑战：脑脊液中（1→3）-β-D-葡聚糖和甘露聚糖抗原检测及脑室穿刺的价值
Med Mycol. 2021 Jan 4;59(1):74-80. doi: 10.1093/mmy/myaa035.
4
Improvement in Diagnosis of Histoplasma Meningitis by Combined Testing for Histoplasma Antigen and Immunoglobulin G and Immunoglobulin M Anti-Histoplasma Antibody in Cerebrospinal Fluid.通过联合检测脑脊液中组织胞浆菌抗原和免疫球蛋白 G、免疫球蛋白 M 抗组织胞浆菌抗体改善组织胞浆菌性脑膜炎的诊断。
Clin Infect Dis. 2018 Jan 6;66(1):89-94. doi: 10.1093/cid/cix706.
5
Aspergillus meningitis in a patient with chronic lymphocytic leukemia.慢性淋巴细胞白血病患者的曲霉性脑膜炎。
J Infect Chemother. 2020 Jun;26(6):622-624. doi: 10.1016/j.jiac.2020.01.012. Epub 2020 Mar 3.
6
Candida species isolated from cerebrospinal fluid.从脑脊液中分离出的念珠菌属菌种。
Folia Microbiol (Praha). 2002;47(2):179-81. doi: 10.1007/BF02817678.
7
Chronic candidal meningitis: an uncommon manifestation of candidiasis.慢性念珠菌性脑膜炎：念珠菌病的一种罕见表现。
Clin Infect Dis. 1994 Jul;19(1):60-6. doi: 10.1093/clinids/19.1.60.
8
Mannan antigenemia in the diagnosis of invasive Candida infections.甘露聚糖抗原血症在侵袭性念珠菌感染诊断中的应用
J Clin Invest. 1976 Nov;58(5):1045-53. doi: 10.1172/JCI108555.
9
[Candida meningitis in childhood. Clinical aspects].[儿童念珠菌性脑膜炎。临床方面]
Minerva Pediatr. 1992 Oct;44(10 Suppl 1):79-83.
10
Candida meningitis possibly resulting from a harpoon injury.念珠菌性脑膜炎可能由鱼叉伤所致。
Eur J Clin Microbiol Infect Dis. 1999 Jun;18(6):454-5. doi: 10.1007/s100960050319.
引用本文的文献
1
Chronic Candida albicans meningoencephalitis in a patient with mantle cell lymphoma: a diagnostic challenge.套细胞淋巴瘤患者的慢性白色念珠菌性脑膜脑炎：一项诊断挑战。
Neurol Res Pract. 2025 Mar 3;7(1):15. doi: 10.1186/s42466-025-00375-2.
2
Case report: Chronic meningitis: a rare entity diagnosed by metagenomic next-generation sequencing.病例报告：慢性脑膜炎：一种通过宏基因组下一代测序诊断的罕见病症。
Front Cell Infect Microbiol. 2024 Apr 19;14:1322847. doi: 10.3389/fcimb.2024.1322847. eCollection 2024.
3
Role of Molecular Biomarkers in the Diagnosis of Invasive Fungal Diseases in Children.分子生物标志物在儿童侵袭性真菌病诊断中的作用
J Pediatric Infect Dis Soc. 2017 Sep 1;6(suppl_1):S32-S44. doi: 10.1093/jpids/pix054.
4
Progress in the Diagnosis of Invasive Fungal Disease in Children.儿童侵袭性真菌病的诊断进展
Curr Fungal Infect Rep. 2017;11(2):35-44. doi: 10.1007/s12281-017-0274-9. Epub 2017 May 2.
5
CNS infections in patients with hematological disorders (including allogeneic stem-cell transplantation)-Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO).血液系统疾病患者（包括异基因干细胞移植）的中枢神经系统感染——德国血液学和肿瘤内科学会（DGHO）传染病工作组（AGIHO）指南
Ann Oncol. 2016 Jul;27(7):1207-25. doi: 10.1093/annonc/mdw155. Epub 2016 Apr 6.
6
Guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children: recommendations from the National Institutes of Health, Centers for Disease Control and Prevention, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics.HIV暴露儿童和HIV感染儿童机会性感染的预防和治疗指南：美国国立卫生研究院、疾病控制与预防中心、美国传染病学会HIV医学协会、儿科传染病学会及美国儿科学会的建议
Pediatr Infect Dis J. 2013 Nov;32 Suppl 2(0 2):i-KK4. doi: 10.1097/01.inf.0000437856.09540.11.
7
The use of mannan antigen and anti-mannan antibodies in the diagnosis of invasive candidiasis: recommendations from the Third European Conference on Infections in Leukemia.甘露聚糖抗原和抗甘露聚糖抗体在侵袭性念珠菌病诊断中的应用：第三届白血病感染欧洲会议的建议。
Crit Care. 2010;14(6):R222. doi: 10.1186/cc9365. Epub 2010 Dec 8.
9
Current status of fungal cell wall components in the immunodiagnostics of invasive fungal infections in humans: galactomannan, mannan and (1-->3)-beta-D-glucan antigens.真菌细胞壁成分在人类侵袭性真菌感染免疫诊断中的现状：半乳甘露聚糖、甘露聚糖及（1→3）-β-D-葡聚糖抗原
Eur J Clin Microbiol Infect Dis. 2007 Nov;26(11):755-66. doi: 10.1007/s10096-007-0373-6.
10
Fungal infections of the CNS: treatment strategies for the immunocompromised patient.中枢神经系统真菌感染：免疫功能低下患者的治疗策略
CNS Drugs. 2007;21(4):293-318. doi: 10.2165/00023210-200721040-00004.
本文引用的文献
1
Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus.定义癌症和造血干细胞移植免疫受损患者中的机会性侵袭性真菌感染：一项国际共识。
Clin Infect Dis. 2002 Jan 1;34(1):7-14. doi: 10.1086/323335. Epub 2001 Nov 26.
2
The prognostic factors of cryptococcal meningitis in HIV-negative patients.HIV阴性患者隐球菌性脑膜炎的预后因素。
J Hosp Infect. 1999 Aug;42(4):313-20. doi: 10.1053/jhin.1998.0610.
3
Clinical significance of Candida species isolated from cerebrospinal fluid following neurosurgery.神经外科手术后从脑脊液中分离出的念珠菌属的临床意义。
Clin Infect Dis. 1999 May;28(5):1139-47. doi: 10.1086/514755.
4
New enzyme immunoassays for sensitive detection of circulating Candida albicans mannan and antimannan antibodies: useful combined test for diagnosis of systemic candidiasis.用于灵敏检测循环中白色念珠菌甘露聚糖和抗甘露聚糖抗体的新型酶免疫测定法：对系统性念珠菌病诊断有用的联合检测方法
J Clin Microbiol. 1999 May;37(5):1510-7. doi: 10.1128/JCM.37.5.1510-1517.1999.
5
Aspergillus meningitis: diagnosis by non-culture-based microbiological methods and management.曲霉性脑膜炎：基于非培养的微生物学方法诊断与管理
J Clin Microbiol. 1999 Apr;37(4):1186-9. doi: 10.1128/JCM.37.4.1186-1189.1999.
6
Prospective study of nosocomial fungal meningitis in children--report of 10 cases.
Scand J Infect Dis. 1998;30(5):485-7. doi: 10.1080/00365549850161494.
7
Nature of Candida albicans-derived carbohydrate antigen recognized by a monoclonal antibody in patient sera and distribution over Candida species.患者血清中一种单克隆抗体识别的白色念珠菌衍生碳水化合物抗原的性质及其在念珠菌属中的分布。
FEMS Microbiol Lett. 1998 Dec 1;169(1):131-8. doi: 10.1111/j.1574-6968.1998.tb13309.x.
8
Comparison of two rapid latex agglutination tests for detection of cryptococcal capsular polysaccharide.两种用于检测隐球菌荚膜多糖的快速乳胶凝集试验的比较。
Am J Clin Pathol. 1998 May;109(5):634-41. doi: 10.1093/ajcp/109.5.634.
9
Serial monitoring of Aspergillus antigen in the early diagnosis of invasive aspergillosis. Preliminary investigations with two examples.曲霉菌抗原的连续监测在侵袭性曲霉病早期诊断中的应用。两个病例的初步研究。
Infection. 1997 Mar-Apr;25(2):86-9. doi: 10.1007/BF02113581.
10
Enolase antigen, mannan antigen, Cand-Tec antigen, and beta-glucan in patients with candidemia.念珠菌血症患者的烯醇化酶抗原、甘露聚糖抗原、Cand - Tec抗原和β - 葡聚糖
J Clin Microbiol. 1996 Aug;34(8):1918-21. doi: 10.1128/jcm.34.8.1918-1921.1996.
Zotero 插件