Salzman Steve H, Moosavy Farid M, Miskoff Jeffrey A, Friedmann Patricia, Fried Gregory, Rosen Mark J
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Beth Israel Medical Center, New York, NY 10003, USA.
J Occup Environ Med. 2004 Feb;46(2):113-22. doi: 10.1097/01.jom.0000111612.68916.d0.
The effects of exposure to the environment around the World Trade Center after the attack of September 11, 2001, are not fully described. We evaluated 240 police first-responders; respiratory symptoms occurred in 77.5% but resolved or improved in around three fourths of subjects by the time of their evaluation (mean 69 days after the attack). Cough was the most common symptom (62.5%). Spirometric abnormalities were mild and occurred in 28.8%. Independent risk factors for abnormal spirometry were previous pulmonary disease or symptoms (adjusted odds ratio, 2.76) and intensity of exposure (AOR, 2.32). Previous pulmonary conditions were associated with obstructive defects (P<0.002). Exposure intensity was associated with a lower forced vital capacity (P<0.03) and a higher prevalence of abnormal spirometry (P<0.03). Officers with dyspnea, chest discomfort, or wheeze were more likely to have abnormal spirometry (P=0.04). A significant minority of officers had symptoms a few months after the exposure. Long-term effects of this respiratory tract exposure will need additional evaluation.
2001年9月11日袭击事件后，接触世界贸易中心周边环境所产生的影响尚未得到充分描述。我们评估了240名警方首批应急响应人员；77.5%的人员出现了呼吸道症状，但在评估时（袭击后平均69天），约四分之三的受试者症状已缓解或改善。咳嗽是最常见的症状（62.5%）。肺功能检查异常情况较轻，发生率为28.8%。肺功能检查异常的独立危险因素为既往肺部疾病或症状（调整比值比，2.76）以及接触强度（调整比值比，2.32）。既往肺部疾病与阻塞性缺陷相关（P<0.002）。接触强度与较低的用力肺活量相关（P<0.03）以及肺功能检查异常的较高患病率相关（P<0.03）。出现呼吸困难、胸部不适或喘息的警官更有可能存在肺功能检查异常（P=0.04）。一小部分警官在接触数月后仍有症状。这种呼吸道接触的长期影响需要进一步评估。
