O'Sullivan F, Rossor M, Elston J S
Western Ophthalmic Hospital, London.
Br J Ophthalmol. 1992 Nov;76(11):660-2. doi: 10.1136/bjo.76.11.660.
Nine young adults (median age 19.5 years) who suffered from amaurosis fugax (AF) are described. The attacks of AF were short in duration and preceded by premonitory symptoms in five cases and by a migrainous headache in two. In five patients the visual loss progressed in a lacunar pattern unlike the 'curtain' pattern characteristic of AF in older patients. Investigation revealed no evidence of an embolic or atheromatous aetiology. In two cases a minor abnormality was found on echocardiography. We conclude that AF in young adults has a different clinical pattern and may have a different aetiology, possibly migrainous, compared with that seen in older patients. The pattern of visual loss in some of the cases suggests that the choroidal circulation rather than the retinal circulation is primarily affected.
本文描述了9名患有一过性黑矇(AF)的年轻成年人(中位年龄19.5岁)。AF发作持续时间短,5例有先兆症状,2例有偏头痛样头痛。5例患者的视力丧失呈腔隙性进展,与老年患者AF特征性的“幕布”样进展不同。检查未发现栓塞或动脉粥样硬化病因的证据。2例经超声心动图检查发现轻微异常。我们得出结论,与老年患者相比,年轻成年人的AF具有不同的临床模式,病因可能也不同,可能与偏头痛有关。部分病例的视力丧失模式表明,主要受影响的是脉络膜循环而非视网膜循环。