Avtandilov G G, Barsukov V S
Department of Pathological Anatomy, Central Institute for Advanced Medical Training, Moscow, Russia.
Zentralbl Pathol. 1992 Nov;138(5):345-9.
Morphological and morphometric studies were conducted into lymphoid and endocrine organs of 259 human adults and infants with pyoinflammatory diseases (PID) and of 300 experimental mice. Informative and correlation analyses of the data thus recorded provided evidence to the effect that in the course of an infection process adaptation and compensation responses were characterized by intensified exchange of information within the immune-endocrine system (IES). Septic courses of PID were found to be accompanied by impairment of inter-organ correlations, increase in information entropy and progressive structural disorganization of the IES.
对259名患有脓性炎症疾病（PID）的成人和婴儿以及300只实验小鼠的淋巴和内分泌器官进行了形态学和形态计量学研究。对所记录数据的信息分析和相关性分析表明，在感染过程中，免疫-内分泌系统（IES）内信息交换加强是适应和补偿反应的特征。发现PID的败血症病程伴有器官间相关性受损、信息熵增加以及IES的渐进性结构紊乱。
